Navegando por Assunto "COVID-19"

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Análise comparativa do padrão tomográfico pulmonar na infecção pelas variantes B.1.1.7 e P.1 do vírus SARS-COV-2
(Centro Universitário do Estado do Pará, 2022) Savino, Beatriz Amaral Costa; Mafra, Eduarda Gabriel; Paes, Andréa Luzia Vaz; Bichara, Cléa Nazaré Carneiro; http://lattes.cnpq.br/2161704040280760; http://lattes.cnpq.br/4364540186589331
Introduction: The SARS-CoV-2 virus quickly spread globally and acquired pandemic status in March 2020, posing a major threat to public health. Since then, it has suffered several genetic mutations, which culminated in multiple waves of disease transmission. Computed tomography (CT) of the chest may be a diagnostic alternative complementary to RT-PCR, to assess pulmonary involvement and assist in the therapeutic approach. Objective: To analyze lung tomographic patterns in the COVID-19 epidemic curves in 2020 and 2021 caused by the B.1.1.7 and P.1 variants of the SARS-CoV-2 virus. Methodology: A cross-sectional, descriptive, analytical and retrospective study was carried out through the evaluation of 360 CT scans of the chest, in a Reference Radiology Service, including patients with COVID-19 in two epidemic periods in an area of the Brazilian Amazon, characterized by lineages B.1.1.7 (Alpha) from April – September 2020 and P.1 (Gamma) from October 2020 – March 2021. Expert Consensus criteria of the Radiological Society of North America (RSNA) were used. In patients older than 18 years of age, of both sexes, the pattern and degree of pulmonary involvement, distribution of lesions, affected segments and other findings on tomography were evaluated. Results: The proportions of patients of different genders (p=0.289) or different age groups (p=0.314) did not vary significantly between periods. In the first period, 70.6% had pulmonary involvement between 10-25% and in the second period only 43.3%. All individuals had ground-glass lesions and the presence of thickening of the interlobular septa was significantly observed in the first epidemic curve (81.9%) (p=0.002). Conclusion: There was a prevalence of women and individuals aged between 45-60 years. 100% of the individuals presented ground-glass lesions and the typical pattern of involvement prevailed in both analyses. The Alpha variant, predominant in the first epidemic curve, presented a higher degree of pulmonary involvement in relation to the Gamma variant, predominant in the second epidemic curve.
Análise da violência contra a criança na pandemia da COVID-19 no Estado do Pará
(Centro Universitário do Estado do Pará, 2023-05-29) Carneiro, Sâmya Maria Brito; Neves, Dilma Costa de Oliveira; Pereira, Ângela Regina Rosa Corrêa; http://lattes.cnpq.br/1342885069761211; http://lattes.cnpq.br/7230812534416350; Oliveira, Kátia Soares de; http://lattes.cnpq.br/7676881940781206; Miranda, Marisa Eiró; http://lattes.cnpq.br/9869549838157176
The SARS-CoV-2 pandemic was characterized by several stressful events with potential to increase the chance of child abuse. The present work aims to analyze the tendency of interpersonal and self-provoked violence against children during the period of the COVID-19 pandemic in the state of Pará. Data was obtained from the Notifiable Diseases Information System (SINAN), under the management of the Department of Epidemiology of Pará Public Health Office (SESPA), in the period from 2018 to 2021, analyzing records referring to the victim (gender, age, color, education, physical disability/disorder), the occurrence (date, city, State, place, number of times the victimization occurred, type of violence and number of aggressors) and to the aggressor (relationship with the victim and use of alcohol by the aggressor). Cases with duplicity, occurrence in other states, failure to fill in more than 50% of the variables and occurrences in which it was impossible to identify the type of aggression were excluded. Statistical analysis was performed using the BioEstat 5.3 program, using descriptive statistics and, for differences between the proportions of subgroups of variables, the non-parametric Chi-square test of adherence for equal expected proportions. A p value < 0.05 (α=5.0%) was accepted as a significance level for the differences. There was a number of 4997 cases of interpersonal and self-provoked violence against children in the state of Pará between 2018 to 2021, with a higher occurrence in 2021 (33.24%) and the most affected age group was from 5 to 9 years old (44.20%), with most cases being sexual assault (65.46%). From 2019 to 2020 there was a decrease (16.54%) in occurrences, with an increase from 2020 to 2021 (49.63%). The victims were mostly girls (71.64%), brown (78.13%), with incomplete primary education (49.83%) and most of the violations were at home (92.34%), being caused mainly by acquaintances. In the records of disability/disorder, “Mental Disorder” was the most present. Most of the agressors had no suspicion of alcohol use (53.31%) and acted alone (81.55%). Revictimization between 2018 and 2021 was equivalent to 63.92%, psychological violence was the highest (146.66%). The 10 cities with the highest number of cases (68.14%) were Belém (34.30%), Ananindeua (7.46%), Altamira (5.40%), Santarém (4.96%), Parauapebas (3 .96%), Barcarena (3.30%), Tucuruí (3.00%), Thailand (2.08%), Abaetetuba (1.92%) and Moju (1.74%). Most of the violence corresponded to sexual violence, predominating in schoolchildren, girls, of brown race/color/ethnicity and with incomplete primary education. “Mental Disorder” was the most registered disability/disorder. Mostly of he aggressors were acquaintances who acted alone, at the victim's residence and with no suspicion of alcohol use. Most of the cases occurred in Belém. There was an increase of aggression reports during the COVID-19 pandemic. It is expected that this work will stimulate discussions and measures in the academic and professional environment for prevention and fight against child abuse in the health area, in order to promote protection and comprehensive care of this group.
Análise da violência contra a pessoa idosa na pandemia da COVID-19 no estado do Pará
(Centro Universitário do Estado do Pará, 2022) Goes, Larissa Mescouto; Sakairi, Sheila Aemy Takemura; Neves, Dilma Costa de Oliveira; Costa, Tanise Nazaré Maia; http://lattes.cnpq.br/4471975369870057; http://lattes.cnpq.br/7230812534416350
The present study’s theme is the domestic violence against elderly people during the covid-19 pandemic in the state of Pará, in order to broaden the debate on the subject and offer theoretical elements that help to better understand the situation of vulnerability of the elderly in the face of the pandemic context in the state. Objective: Analyze the occurrence of this type of violence and the variables that involve it in general. Methodology: The type of research was ecological exploratory time series, with data obtained from the Notifiable Diseases Information System (SINAN) that were used under the management of the Department of Epidemiology of the State Department of Public Health of Pará (SESPA). The variables analyzed were gender, age, color, schooling, marital status, type of physical disability, mental disability, municipality of occurrence, place of occurrence, revictimization, type of violence, number of aggressors, relationship with the person victimized by aggression and alcohol use by the aggressor, and the exclusion criterion included duplication, occurrence in other states and cases with no filling of more than 50% of the variables mentioned above. Results: The data showed a significant increase in the number of records of violence in the period under analysis (2018 to 2021), with more cases related to females in the age group between 60-70 years, brown color, with elementary school education and married marital status. In addition, a predominance of psychological and hanging violence was identified, which occurred mostly from individuals unknown to the victim, in their residence itself and by one individual only. There was also an important recurrence of cases, which occurred more frequently in the urban area and with the aggressor being mostly male and often drunk during the episodes of aggression. Finally, it was found that there was no strong correlation between the Municipal Human Development Index and the occurrence of violence. Conclusion: Violence against the elderly is a public health, security, educational and economic problem that requires state actions to modify the current scenario, especially in the post-pandemic context, considering the increase in the fragility and vulnerability of this population in question.
Análise do perfil epidemiológico auto-referido em amostra de brasileiras grávidas durante a pandemia de COVID-19: um estudo transversal (2020-2021)
(Centro Universitário do Estado do Pará, 2021) Pinto, Hana Paula Campos; Pereira, Isabela Rosita da Silva; Teixeira, Cláudio Eduardo Corrêa; http://lattes.cnpq.br/7448998858430931
Introduction: In early 2020, the world began to experience impacts of different magnitudes at different levels and activities of human society, due to the occurrence of the pandemic of a new coronavirus (SARS-CoV-2), which causes a systemic disease, now recognized as COVID-19. In this context, the acquisition and interpretation of epidemiological data, many of a nature never worked on before, became essential for making preventive decisions and for containing the spread of the disease, as well as for clarifying the real impacts of the pandemic. Objective: To carry out an exploratory survey of the impact suffered by Brazilian pregnant women during the COVID-19 pandemic. Methodology: This study is characterized as observational, cross- sectional, exploratory. Data were obtained from a questionnaire distributed by social networks to all Brazilian states from April 2020 to July 2021. Among more than 60,000 respondents, 500 pregnant women reported on the main aspects of impact on their lives during the pandemic: with how many co-inhabitants share their homes, if they already have children, if they managed to isolate and distance themselves adequately, if they had to work to support themselves, if they were tested and/or vaccinated, among several other aspects. All data were organized, cleaned and worked using the statistical computer program R. Results: The results show that most pregnant respondents are between 30-39 years old, live in the southeast (SP), in a home with a single family (3 people), formed by only young people and adults (or with few elderly and more children), they think they do not need to be tested, they did not have any symptoms, they suffered from anxiety, they work in places where prevention measures are implemented, they avoid crowding, they think the governmental measures taken are insufficient, they are in favor of lockdown, but in favor of the opening of sporting events, they did not have a significant economic impact, they think that having to take care of children makes isolation difficult, and they do not have other risk factors for COVID-19 serious. Conclusion: We conclude that, in general, Brazilian pregnant women in our sample were impacted differently by the pandemic, showing a very evident preventive behavior. This raises the question of whether such behavior does not explain the low number of pregnant women among the cases and deaths recorded during the pandemic.
Análise epidemiológica do impacto da pandemia da COVID-19 nas notificações da hanseniase na região norte
(Centro Universitário do Estado do Pará, 2023-05-30) Falqueto, Alessandra Andrade; Neves, Dilma Costa de Oliveira; Magno, Ismaelino Mauro Nunes; http://lattes.cnpq.br/3841081216551678; http://lattes.cnpq.br/7230812534416350; Santos, Eliane Regine Fonseca; http://lattes.cnpq.br/3837797857505891; Matos, Haroldo José de; http://lattes.cnpq.br/9830983900880582
Leprosy is an infectious disease caused by Mycobacterium leprae, affecting mainly the skin and peripheral nerves, with a chronic course. Although the leprosy detection rate showed a downward trend between 2015 and 2021, this finding may be related to the effects of the lower number of diagnoses caused by the overload of health services and restrictions during the covid pandemic -19. To analyze the impact of the covid-19 pandemic on leprosy notification in the North of the country, between the period 2015 to 2021. Descriptive study of leprosy cases, occurring in the North Region, using existing records in the Information System of Notifiable Diseases made available to the public by the Department of Informatics of the SUS, notified in the period from 2015 to 2021. The TABNET tool was used for extraction of the data and a simple descriptive statistical analysis was performed, with the aid of the BioEstat 5.3 program. The number of cases notified in Brazil and in the North Region of the country had an important reduction in the Covid-19 pandemic, in the years 2020 and 2021. Even with the lowest number of notifications during this period, the North Region is still considered with a high rate endemicity of leprosy. It is believed that the Covid-19 pandemic had a negative impact on notifications of new cases of leprosy and that over the next few years there may be a significant increase in cases due to underreporting during the period of the Covid-19 pandemic.
Associação entre o pertencimento a grupos de risco para COVID-19 e o estado emocional autorreferido de cidadãos brasileiros durante a pandemia de 2020-2021: um estudo transversal
(Centro Universitário do Estado do Pará, 2021) Sizo, Marcele de Pinna; Fukushima, Vanessa Iukari; Teixeira, Cláudio Eduardo Corrêa; http://lattes.cnpq.br/7448998858430931
Introduction: In early 2020, the world began to experience impacts of different magnitudes at different levels and activities of human society, due to the occurrence of the pandemic of a new coronavirus (SARS-CoV-2), which causes a systemic disease, now recognized as COVID-19. In this context, the acquisition and interpretation of epidemiological data, many of a nature never worked on before, became essential for preventive decision-making and for containing the spread of the disease, as well as for clarifying the real impacts of the pandemic. Objective: To investigate whether there is a correlation between being in a risk group for severe COVID-19 and having some impairment in emotional status related to pandemics. Methodology: This study is characterized as observational, cross-sectional, exploratory. Data were obtained from a questionnaire distributed by social networks to all Brazilian states from April 2020. Among more than 60,000 respondents, 45,025 informed if they are part of any risk group for serious disease and if they present any it harms your emotional state. Correlation between these datasets were carried out using linear autocorrelograms. All data were organized, cleaned and worked using the statistical computer program R. Results: The results show that, in general, there is no significant correlation between being from a risk group and having an impaired emotional state, regardless of whether the citizen is an adult or elderly, female, male or other. Conclusion: We conclude that the impact on mental health generally related to the pandemic must be associated with factors other than the presence of risk factors for serious illness.
Atuação da fisioterapia na Síndrome Respiratória Aguda Grave em pacientes com COVID-19: uma revisão sistemática
(Centro Universitário do Estado do Pará, 2021) Souza, André Felipe Gonçalves; Miranda, Blenda Danielly Libdy; Lima, Gabriela Martins de; http://lattes.cnpq.br/9186298523685237
This review seeks to identify the main ways in which physical therapy acts in severe respiratory syndrome in patients with COVID-19. This is a systematic literature review, with selected studies in English and Spanish, covering the years 2019 to 202l. The search was carried out through the scientific databases, PubMed, MEDLINE, SciELO, PEDro and LILACS, with the descriptors phisiotherapy, SRAG, COVID-19. Twentytwo articles were included for analysis, where resources such as early mobilization; electrical stimulation; oxygen therapy; prone position and non-invasive mechanical conditions (NIV) were the most cited. Physiotherapy worked both in the short term, in intensive care, and in the long term, seeking to reduce the time of mechanics and hospital stay, as well as avoiding complications and improving the functionality of patients. During the searches in the articles, although there is a vast collection about the performance of respiratory physiotherapy, there are few studies related to rehabilitation in patients with SARS; there is a need for better studies in this area. Furthermore, there were contradictions regarding the use of Non-Invasive Mechanical Ventilation in patients affected by COVID-19 respiratory complications, a fact that may be directly related to the clinical outcome of these patients.
Avaliação dos sistemas de informação na pandemia da COVID–19
(Centro Universitário do Estado do Pará, 2022-06-09) Gadelha, Gabriel Ferdinando Costa; Macedo, Robson Oliveira; Silva, Yuri Henrique Monteiro da; Dias, Suzane Alfaia; http://lattes.cnpq.br/9675395702501834; Girotto, Pedro Henrique Sales; http://lattes.cnpq.br/0421749067951878; Melo, Ricardo Rodrigo Marinho; http://lattes.cnpq.br/4312449494921369
Keeping informed is essential for problem solving, due to the high number of accumulated data, information systems were developed to ensure not only the collection, but also the standardized management and sharing of information. In 2020, the COVID-19 pandemic caused chãos around the world, causing governments to seek solutions to end this problem. The high number of new cases of the disease, deaths and recovered daily led to the creation of platforms such as websites and applications to inform and guide the population, making information systems important in this fight. In this article, 6 of these platforms were selected, in order to highlight their use in the pandemic, initially identifying their main characteristics, followed by the creation of comparative tables that pointed out relevant information such as the focus of each platform, the form of access, as well as problems encountered, these and other points were developed following criteria, which led to the choice of each analyzed platform. With this, it was observed that knowledge about the use of health information systems is important, however the lack of initial information about the disease, as well as political and social differences made it difficult to collect data for the creation of platforms, pointing out that many Countries need to rethink their ways of analyzing and acting in the face of problems such as the COVID-19 pandemic.
Borali – aplicativo mobile para localização de vendedores ambulantes de alimentos
(Centro Universitário do Estado do Pará, 2021) Silva, Jordinei Gadelha da; Larrat, Lucas Eugenio de Souza; Macedo, Tales de Oliveira; Luz, Victor Cassio Viana da; Ribeiro, Moshe Dayan Sousa
Millions of Brazilians have in their routine the habit of eating meals outside the home and in new places, and among this routine, often there are street vendors, with their meals or snacks. However, it has become increasingly difficult to obtain information about sellers and locate them on a day-to-day life, due to the decrease in the number of street vendors due to the restrictive measures taken to combat COVID-19. This factor helps people not be able to find the street vendors they were used to or new sellers. Therefore, this work aims to create a mobile application capable of displaying street vendors and informing the user about them, as well as charting a route, simply and quickly, helping in its location and orientation. During the development of this project, it was observed the difficulty in getting the necessary information regarding street vendors. Therefore, a data collection was carried out on street vendors. This work seeks a practical and simple way to find these street vendors.
Coronavírus interfere na qualidade de vida e ansiedade na Esclerose Lateral Amiotrófica
(Centro Universitário do Estado do Pará, 2021) Torres, Eduarda Vieira; Oliveira, Silvia Maria Sobral; Pereira, Carolina Veiga; Rocha, Larissa Salgado de Oliveira; Sobral, Luciane Lobato; http://lattes.cnpq.br/4916750587369204; Rocha, Rodrigo Santiago Barbosa; http://lattes.cnpq.br/4119162366965074
On Amyotrophic Lateral Sclerosis (ALS) the degeneration of motor neurons causes, due to the interference of nerve impulses transmission, the functionality commitment and consequently the individuals’ quality of life (QF). Although, on the COVID-19 pandemic context cause by social isolation, there was the reinforcement of these functional disorders raising to detrimental psychological conditions like anxiety associated with QF. To assess if the social isolation due to COVID-19, affected the axiety and QF levels on patients with ALS. Eighteen individuals with average age of 46,72 ± 14,09 years old, and average diagnosis time of ALS of 2,8 ±1,75 years, were assessed using the Mini Mental State Exam (MMSE), the Amyotrophic Lateral Sclerosis Assessment Questionnaire (ALSAQ-40/BR), Hamilton Anxiety Rating Scale (HAM-A) and clinic-epidemiological questionnaires. Descriptive analysis, Shapiro Wilk test and Pearson’s correlation were used. On MMSE the individuals got average score of 27,33±1,90. It was observed in ALSAQ-40/BR decreased QF (70,03 ± 23,17) and on HAM-A scale 50% of the individuals showed anxiety. However, there was no significant correlation between HAM-A and ALSAQ40/BR (p=0,07). On this study, both questionnaires indicated a decreasing in QF and anxiety presence on the individual with ALS during the COVID-19 pandemic period, even though no correlation among the analyzed objects was found. It is indicated the monitoring during interval periods to define the damages from social isolation and by attendance therapy restriction as physical therapy to preserve the QF.
Efeito protetor do uso de bloqueadores de receptores de angiotensina 2 contra desfechos graves da COVID-19 em pacientes hipertensos: revisão sistemática com metanálise
(Centro Universitário do Estado do Pará, 2022-11-07) Miranda, Anna Luiza Alves de Oliveira; Beltrão, Letícia Viana Martins; Texeira, Cláudio Eduardo Corrêa; http://lattes.cnpq.br/7448998858430931; Maia, Matheus Rocha; http://lattes.cnpq.br/6118052846256806; Pereira, Raphael do Nascimento; http://lattes.cnpq.br/4495343513171099
There are several records in the literature that show the non-association between the use of antihypertensive drugs that inhibit the action of angiotensin II (ANGII) and the occurrence of serious outcomes of COVID-19 in hypertensive patients, which suggests that these drugs potentially exert a protective effect. However, there are no studies in the literature that have investigated this potential considering in an isolated way the effect of different classes of these antihypertensive drugs. Analyse if the use of ANGII type I receptor inhibitors (ARBs) is more protective than that of Angiotensin I Converting Enzyme (ACEi) inhibitors against critical COVID-19 outcomes in hypertensive patients. A systematic review was carried out with a random effect meta-analysis, following the PRISMA model (Preferred Reporting Items for Systematic Reviews and Meta-Analyzes), and using the PubMed, Lilacs and Scielo platforms to collect papers. Twelve of 122 studies were selected, totaling 130,243 patients. In the data analysis, treatment with ARB was considered as intervention/exposure and treatment with ACEI as control/non-exposure. The I2 statistic was used to measure the heterogeneity among the selected works. The results show that, although statistically it is not possible to prove the hypothesis, the summary statistics show a clear trend of: greater hospital admission of patients using ACEI (Standardized Mean Deviation [SMD]: -0.16, interval of 95% confidence [95%CI]: -0.34 to 0.01); higher number of ICU admissions of patients using ACEI (DMP: -0.28, 95%CI: -0.63 to 0.06); higher number of deaths of patients using ACE inhibitors (DMP: -0.15, 95%CI: -0.39 to 0.08). It was not possible to associate concomitant deaths with critical events with the use of ARBs or ACEIs (DMP: -0.10, 95%CI: -0.37 to 0.17). Statistically, it was not possible to associate, in an isolated way, the use of antihypertensive drugs that inhibit the action of ANGII with the protective effect against serious outcomes reported in the literature. However, it was possible to observe a protective tendency for the use of ARBs.
Fadiga crônica como sequela psiquiátrica pós COVID-19 na comunidade acadêmica do Campus Dr João Paulo Valle Mendes em Belém-PA
(Centro Universitário do Estado do Pará, 2022) Messias Junior, André; Nogueira, Victor Dias; Santos, Eliane Regine Fonseca; http://lattes.cnpq.br/3837797857505891
INTRODUCTION: the impact of Sars-CoV-2, which causes covid-19, in the current context is easily perceptible in view of its worldwide unfolding resulting from its high transmissibility that caused the 2020 pandemic. Its repercussion in international health has encouraged the identification of its physical and psychiatric symptoms in affected patients, aiming at the creation of appropriate conducts to combat it. However, it is noted that the virus does not only have implications during the period of infection, but also psychiatric consequences in the post-infection course, especially chronic fatigue, whose consequences may be influenced by several variables, such as the context of the pandemic and the severity of the infectious condition. OBJECTIVES: to identify the prevalence of chronic fatigue among students, teachers and employees who had covid-19, relating them to possible individual variables that could have influenced post-covid symptoms, if any. METHODOLOGY: data collection was carried out at Campus João Paulo do Valle Mendes of Cesupa through the availability of a psychosocial questionnaire that will use 10 items from the Fatigue Assessment Scale (FAS), which is self-administered. This scale was distributed through the Google Forms platform, aiming at the convenience of respondents. Data analysis was performed in an Excel spreadsheet and analyzed using the BioEstat version 5.3 program. RESULTS: A sample of 237 volunteers was used. Of these, 187 had COVID-19, including 118 students, 63 teachers and 6 employees. Most individuals are in the 20-39 age range and are predominantly female. It was found that 18.7% of those who had covid-19 had generalized anxiety disorder, which is the most prevalent disorder. With regard to the severity of the covid-19 condition, most of those who had fatigue in the moderate to severe stages in the post-infection period stated that they had suffered from a more severe form of the disease, with the percentages being equal between student teachers and employees. DISCUSSION: the present work demonstrates a relationship between the presence of psychiatric comorbidities and sequelae of post covid-19 fatigue, as evidenced by other authors, however, it reveals a discrepancy in relation to the occurrence of fatigue, which in accordance with the literature produced in the pandemic period, was more prevalent among women and older individuals. CONCLUSION: students and professors would have a certain parity in mild manifestations of fatigue, but students are more likely to evolve to moderate forms. Post-covid-19 fatigue proved to be more common in young people, having no relation to females. Psychiatric comorbidities predispose to acquiring the disease and later developing its sequelae in more severe forms. Finally, the severity of the covid-19 condition provides a greater chance of developing more serious psychiatric sequelae.
Ganglioneuroblastoma em adolescente: incidentaloma adrenal pós-COVID 19 - um relato de caso raro
(Centro Universitário do Estado do Pará, 2021) Azevedo, Andressa Lima; Ferreira, Jéssika Araújo; Caldato, Milena Coelho Fernandes; http://lattes.cnpq.br/9477878606835309
Introduction: Ganglioneuroblastoma (GNB) is a rare malignant tumor of the adrenal gland. Symptoms depend on the location of the mass effect or the existence of the metastasis. As for the diagnosis, tumors of the neural crest in adults are rare and there is a difficulty in differentiating them only by imaging exams. Objective: To report a case of rare adrenal pathology with an incidence of less than five cases per 1,000,000 children, discovered after Computed Tomography of the Chest performed as a protocol of the COVID-19 disease, making a comparison with the cases reported in the world literature. Method: This is a rare case report study associated with a review of articles published in the world literature on the topic of ganglioneuroblastoma in adults. Case report: We present the case of a previously healthy 18-year-old man was diagnosed with Covid-19 and performed a chest Computed Tomography (CT) scan that showed an incidentaloma described as an oval formation in the right retroperitoneum, anterior to the adrenal. An endocrinologist evaluated the patient with a complete normal physical examination, as well as a hormonal laboratory that proved to be normal. Specialist indicated diagnostic excision, a procedure performed laparoscopically. The pathological examination consisted of a right adrenal and a nodular mass. With diagnosis of GNB intermixed subtype. Conclusion: The patient in the reported case does not fit the disease presentation pattern. Few data are available on the diagnosis and treatment of adults with GNB, making clear the importance of case report publications on the subject.
Os impactos da COVID-19 no atendimento do pré-natal e puerpério em uma Unidade Básica de Saúde
(Centro Universitário do Estado do Pará, 2023-05-31) Valois, Ana Fabrícia Baetas; Ferreira, Ana Flávia Lobato; Romeiro, Janaína Cunha; Coelho, Érica Furtado Azevedo; http://lattes.cnpq.br/5221363260090560; http://lattes.cnpq.br/5894499630718939; Almeida, Cibele Maria de; http://lattes.cnpq.br/7062493789289046; Souza, Ivete Moura Seabra de; http://lattes.cnpq.br/5318491010793081
Evaluate the repercussions of the COVID-19 pandemic in an approach to prenatal and postpartum care in a Basic Health Unit. It is about a crosssectional, prospective and observational study of an analytical-descriptive nature with a quantitative approach, that will be carried out at the Paulo Frota Health Unit, located in the neighborhood of Cidade Nova II, in the municipality of Ananindeua, in the region metropolitan of Belém. Of the 46 patients evaluated in the first prenatal period, 12 were also evaluated in the puerperium, while of the 53 patients evaluated in the pandemic period, 10 were also evaluated in the puerperium. It was noted that both in the pre-pandemic period and during the period, the number of people without continuity in puerperal care was high, but with no significant difference between the periods 2017-2019 and 2020-2022. It was observed that both in the pre-pandemic period and during it, the number of patients without continuity in puerperal care was high. As for the age group, the most frequent age was 18 to 25 years, followed by stable union as the most prevalent family situation and having high school as the most observed education. In addition, regarding gestational planning, there was an increase in unplanned pregnancies when the two periods are compared. Regarding the verification of vaccination against Covid-19, a low adherence of these pregnant women was noticed. In reference of regard to multidisciplinary assessment, dentistry and nutrition were the ones with the highest prevalence of referrals. Therefore, despite the great impact of the Covid-19 pandemic, this work showed an immense fragility that already exists in the clinical follow-up of these women, being of fundamental importance and social relevance the adequacy and maintenance of a follow-up within the standards recommended by the various protocols and recommendations from Ministry of Health and Brazilian Federation of Gynecology and Obstetrics.
O impacto da pandemia da COVID-19 no perfil clínico dos pacientes diabéticos atendidos no Centro de Especialidades Médicas do Cesupa no ambulatório de hiperdia durante o período de 2019 a 2021
(Centro Universitário do Estado do Pará, 2022) Covre, Paula Mendonça; Cavaléro, Talyssa Melo de Sousa; Bastos, Fabíola de Arruda; http://lattes.cnpq.br/9386935778704228
Diabetes Mellitus type 2 is a chronic disease resulting from a state of hyperglycemia and peripheral insulin resistance, which gained notoriety during the COVID-19 pandemic because it is a comorbidity of risk for the development of this infection, as well as other chronic diseases. Consequently, the control of glycemic levels of diabetic patients faced obstacles embedded by the chaotic scenario that developed in the pandemic period, such as: social isolation, decreased supply of basic health services, difficulty in accessing consultations and elective procedures. Therefore, it is important to conduct a study that analyzes the change in the clinical profile of diabetic patients during the pandemic period. To leverage data that translates the change in the clinical profile of diabetic patients followed at the Hiperdia outpatient clinic of the Center for Medical Specialties of CESUPA (CEMEC) in the period of 2019 to 2021. This is a descriptive cross-sectional analytical study conducted by collecting data from medical records provided by the Center for Medical Specialties of CESUPA (CEMEC). Regarding the epidemiological profile, the majority are female (63.9%) aged 60 to 89 years (57.4%). Regarding the anthropometric variables analyzed, weight and BMI, no significant changes were found, both in BMI (p=0.124), or weight (p=0.244), between 2019 and 2020; between 2020 and 2021, there were also not many changes. In the present study, when comparing the number of drugs between 2019 and 2020, there was an increase (Mean ± SD:1.5 ± 0.7 vs 1.7 ± 0.8; P=0.050). Regarding the number of tablets, there was also an increase between 2019 and 2020 (Mean ± SD: 3.5 ± 1.7 vs 3.9 ± 1.7; P<0.001). Between 2020 and 2021, the number of medicines did not differ significantly (p=0.881) nor the number of tablets (p=0.814). It was possible to observe that the daily dose of metformin between 2019 and 2020 showed an increase (Mean ± SD: 1607.5 mg ± 686.5 mg vs 1761.3 mg ± 673.8 mg; P=0.019). Regarding laboratory tests, between 2019 and 2020 there was low difference between fasting blood glucose values (Mean ± SD: 134.4 ± 37.4 vs 144.2 ± 59.3; P=0.348), postprandial glycemia (Mean ± SD: 177.0 ± 76.7 vs 154.8 ± 40.3; P=0.384) and glycated hemoglobin (Mean ± SD: 7.0 ± 1.3 vs 6.9 ± 2.4; P=0.315). Before these results, it is possible to conclude that during the pandemic there was an adjustment in the therapeutic plan of the followed-up patients, with an increase in the number of medications and tablets. In addition, most patients improved glycemic levels by fasting glycemia, postprandial glycemia and glycated hemoglobin. Thus, it is ensured that this work is of great value, because it is found that despite the obstacles faced by patients during the pandemic, diabetes control was achieved.
Perfil de mulheres vítimas de agressão que foram a óbito no período pré e pandemia no estado do Pará no ano de 2018 a 2020
(Centro Universitário do Estado do Pará, 2023-11-07) Rodrigues, Ana Luísa Damasceno; Reis, Lilian Rose Martins; Luz, Patrícia Bárbara Pinho da; Magno, Ismaelino Mauro Nunes; http://lattes.cnpq.br/3841081216551678; http://lattes.cnpq.br/2182892468197821; Rodrigues, Brenda Diniz; http://lattes.cnpq.br/6746290429073526; Miranda, Rayssa Pinheiro; http://lattes.cnpq.br/1849222504854523
Aggression followed by female death is a problem that affects social, cultural and public health spheres, with male chauvinism, patriarchy and misogyny being one of the triggering factors for the deaths of women due to aggression in the world. Currently, Brazil is classified as the fifth country with the highest number of these deaths, affecting victims of different age groups, ethnicities, marital status and education. To analyze the profile of deaths of women due to aggression in the pre and pandemic period in the state of Pará. This study used a combined methodological approach, involving bibliographical research, quantitative analysis and descriptive analysis. The data source used was the Mortality Information System (SIM) of the Datasus Program, covering the period from 2018 to 2020. A total of 3.971 cases of death due to aggression against women that occurred in the state of Pará were registered, and in 2018 there were specifically 1.736 cases, in 2019 there were 1.217 and in 2020 there were 1.018. It was noted that, in the 3 years analyzed, Belém was the municipality with the highest number of death notifications, with 82 in 2018, 55 in 2019 and 34 in 2020. Most victims were of brown ethnicity, single, aged between 20 and 29 years old and with 4 to 7 years of age. schooling. Cases were more prevalent in their own household. As for the cause of death, the most frequent was due to aggression by a sharp or penetrating object. There was an increase in the number of cases of death by aggression in the state of Pará during the Pandemic period due to the greater coexistence of the aggressors with the victims at home. Due to this, there was also a greater difficulty for women to report such events, favoring the occurrence of underreporting. It is noteworthy that many victims, for not having knowledge about the legal means of defense, become more susceptible to such unfortunate events. Thus, the study addressed in this work demonstrates the importance of recognizing such a problem in society and the need for multidisciplinary actions to combat such an occurrence in the state of Pará.
Perfil do número de óbitos por COVID-19 em profissionais de saúde no estado do Pará
(Centro Universitário do Estado do Pará, 2021) Lima, João Paulo Cardoso de; Tappembeck, Wigson Yan dos Santos; Magno, Ismaelino Mauro Nunes; http://lattes.cnpq.br/3841081216551678
Introduction: The coronaviruses are a group known since the mid-1960s. In December 2019, the press in Wuhan, China, began reporting cases about a mysterious virus that caused respiratory injuries, being named SARS-CoV-2. The most vulnerable organs to SARS-CoV-2 include lungs, heart, esophagus, kidneys, urinary bladder and the ileum. The human-to-human transmissions occurs through close contact with respiratory droplets produced when an infected person breaths, sneezes or coughs. The clinical picture may vary from a mild and asymptomatic presentation to a severe presentation, including septic shock with respiratory failure. The majority part of the cases in which death occurred were in patients with some pre-existing clinical condition of risk and/or the elderly Objectives: To identify the epidemiological profile of deaths from Covid-19 in the population of healthcare professionals in the State of Pará. Methodology: An observational, descriptive, ecological study was performed, based on publicly available data from Ministry of Health, Pará State Public Health Secretariat, Regional Medical Council of the State of Pará and Regional Council of Nursing of the State of Pará. A Program was used to collect the interesting data, classified with CID-10 U07.1 or B34.2, as well as occupation, age, gender and race/ color, between December 2019 and July 2021. Results: We detected a percentual of health professionals in state of Pará who were affected by Covid-19 and whose Evolution was death. In this group, most of the deaths were related to doctors, with nurses in second place and nursing technicians coming third. The sociodemographic variables showed that the Metropolitan Region I was the most affected. Furthermore, the brown population and the 60 – 69 aged population were the most affected among these professionals. Conclusion: Among the professionals who evolved to death, doctors are among the most affected, being followed by nursing technicians and nurses. Regarding the issue of ethnicity/race and gender, it was found that men, of mixed ethnicity and coming from Metropolitan Region I, accounted for a greater number of affected individuals. The offer of individual protection equipment to health professionals in the state of Pará is an issue that must be discussed by the health community and the respective authorities, since that, without this equipment, the professionals present a greater risk of becoming infected and dying. In addition, the tools’ quality for data collection about the pandemic is an aspect to be observed by public agencies since many data and knowledge are difficult to access or only partially available to Society in general.
Pesquisa impacto Brasil COVID-19: um estudo transversal sobre o estado de saúde mental de brasileiros durante a pandemia
(Centro Universitário do Estado do Pará, 2022-05-20) Sousa, Thalita Duarte; Silva, Serginara Cristina Flexa Pereira da; Teixeira, Cláudio Eduardo Corrêa; http://lattes.cnpq.br/7448998858430931; Carvalho, Walther Augusto de; http://lattes.cnpq.br/0789028145294047; Neves, Dilma Costa de Oliveira; http://lattes.cnpq.br/7230812534416350
COVID-19 is an infection disease caused by the SARS-CoV-2 virus, which was responsible for the pandemic that began in 2019. The infection sickened more than one million people, compromising physical and mental health, the latter one being the most affected. To evidence the impact of the changes caused by pandemic period of the COVID-19 on the mental health of Brazilian citizens. Cross-sectional observational study of an analytical nature with a quanti-qualitative approach, developed in the municipality of Belém-PA. Men and women over 18 years of age participated in the study. The data was obtained through the application of a questionnaire divided into 6 sections that addressed different dimensions related to the experience of Brazilian citizens during the pandemic by COVID-19. In the alcohol consumption variable a greater predominance was observed in younger males. In other variables such as loneliness, sadness, anxiety, stress and use of technologies, was discretely higher in younger women. No correlation was observed between the psychosocial variables and mobility forms. Far beyond the dichotomy of the presence or not of the virus infection, the COVID-19 pandemic interferes in all social spheres and its sequels echo in different aspects of life.
Produção de vacinas de RNA mensageiro na pandemia de COVID-19: advento de novas aplicações em tratamentos de saúde
(Centro Universitário do Estado do Pará, 2023-05-31) Silva, Ana Luiza Marques de Miranda; Araújo, Ana Paula Sales de; Oliveira, Ciane Martins de; http://lattes.cnpq.br/1198411524202572; Barreto, Irma Cecília Douglas Paes; http://lattes.cnpq.br/5300419810944817; Lima, Jackson Cordeiro; http://lattes.cnpq.br/5898669844844564
Modern vaccines developed using messenger RNA (mRNA) technology are highly accurate formulations designed to stimulate the production of a variety of antigenic properties in the user in order to activate adaptive immunity. This enables the use of such technology in the research of vaccines against several infectious diseases, such as hepatitis C, Acquired Immunodeficiency Syndrome (AIDS), malaria, tuberculosis, in addition to chronic diseases, such as some types of cancer. Such vaccines were an efficient alternative in the fight against COVID-19 and have remarkable characteristics, such as the versatility of their applications and the ability to encode and express virtually any type of protein. Like this, this work is justified by the need to know the potential applications of this technology in clinical practice and in the search for effective alternative solutions in the fight against infectious and chronic diseases. A systematic literature review was carried out, including texts in portuguese or english from 2019 to the present day and original texts published before 2019, searched in databases such as Science Direct, US National Library of Medicine, Scielo, Pubmed and National Institute of Industrial Property. At the end of the study, it was possible to understand the range of applications that mRNA technology can bring to medicine, as well as influence the prognosis of various diseases. While the data are promising, it is important to continue to carefully monitor and evaluate the long-term adverse effects of mRNA technology in large-scale studies, as safety and efficacy in humans are crucial issues that must be addressed prior to widespread clinical application of the mRNA technology.