Trabalho de Conclusão de Curso - TCC
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Item O paradigma da eficácia da quimioterapia em associação com diferentes tratamentos adjuvantes no tratamento do retinoblastoma: uma revisão sistemática da literatura(Centro Universitário do Estado do Pará, 2025-05-27) Luz, Ana Flavia Cardoso; Alves, Carolina Ferreira; Costa, Tanise Nazaré Maia; Araújo, Rita Helena Vallinoto; http://lattes.cnpq.br/4089453459357945; http://lattes.cnpq.br/4471975369870057; Silva, Carolina Trindade Pinto da; http://lattes.cnpq.br/1462166625345308; Guerreiro, Maiana Darwich Mendes; http://lattes.cnpq.br/6008305625565373; Coutinho, Igor Jordan Barbosa; http://lattes.cnpq.br/1282626226442845The treatment of retinoblastoma, the most common malignant eye tumor in children, has considerably evolved with the combination of chemotherapy and adjuvant treatments. This study conducted a systematic literature review to analyze the effectiveness of chemotherapy associated with different adjuvant therapies, such as thermotherapy, cryotherapy, and immunotherapy, in controlling retinoblastoma. Through a comprehensive search strategy in electronic databases such as Scielo Brasil, PubMed, Google Scholar, Web of Science, and the Capes Journals Portal, 16 relevant studies published between 1988 and 2024 were identified and selected. The inclusion criteria, such as publication date, language (English or Portuguese), and relevance to the theme of this work, were rigorously applied to ensure the relevance of the selected articles. The selection of studies was carried out in two stages: initially, by reading the titles and abstracts, and then by fully evaluating the texts to verify their eligibility based on the established criteria. The qualitative and quantitative analysis of the extracted data revealed patterns and trends regarding the effectiveness of these therapeutic combinations. The methodological quality of the selected studies was evaluated using standardized tools, such as the Newcastle-Ottawa scale for observational studies. The results indicated that integrating chemotherapy with adjuvant treatments significantly improved clinical outcomes, promoting better vision preservation and reducing recurrence rates. However, variability in treatment response and the need for an individualized approach were highlighted as fundamental factors for therapeutic success. This systematic review reinforced the importance of a multimodal approach and continuous research to improve therapeutic strategies in the treatment of retinoblastoma, pointing to the need for future investigations that can consolidate and innovate clinical practices in this field.Item Perfil clínico epidemiológico de pacientes com doenças inflamatórias intestinais atendidos pelo Centro de Especialidades Médicas do CESUPA (CEMEC) no período de agosto de 2021 a março de 2024(Centro Universitário do Estado do Pará, 2025-05-26) Cordeiro, Ananda Paula da Silva; Freitas, Elaine Vilhena de; Mendes, Yasmin Batista; Sampaio, Regiane Miranda Arnund; Rodrigues, Ana Paula Guimaraes; http://lattes.cnpq.br/8714469084529838; http://lattes.cnpq.br/4904370452637372; Valente, Tárik Olívar de Nunes; http://lattes.cnpq.br/9516550105434600; Corrêa, Aida Lopes Sirotheau; http://lattes.cnpq.br/8922093304432676Introduction: Crohn's disease and ulcerative colitis are the two main types of inflammatory bowel disease (IBD). This group of chronic diseases draws attention due to the large number and variety of intestinal and extraintestinal manifestations, and the profile of these patients in the Amazon region has been little studied. Due to the large number and severity of clinical signs and symptoms, IBD presents considerable impairment of the social, economic and emotional performance of the affected individual. Thus, the present study aims to identify the clinical-epidemiological profile of the population treated at the Gastrointestinal Pathology Outpatient Clinic of the Medical Specialties Center of CESUPA (Higher Education Institution of the city of Belém-PA), understanding that this knowledge allows the development of actions aimed at improving the quality of life of individuals. Methods: This is a descriptive, observational, cross-sectional, and retrospective study focusing on the analysis of medical records of patients with IBD, observing the variables of the clinical and epidemiological profile of the patients followed from August 2021 to March 2024. Results: 32 patients with IBD were identified, with 54.8% having UC, 21.4% having CD, with a predominance of females (78.1%), with an age range of 20-30 years (21.9%), with regard to the work occupation recorded in medical records, there is a predominance among retirees (18.8%), with a high prevalence of comorbidities (62.5%), with 62.5% being sedentary. Regarding disease activity, 56.3% were active, 34.4% in remission, and 9.4% not informed. The most commonly used therapy was mesalazine (43.8%), followed by azathioprine in 37.5% and prednisone in 15.6%. CT enterography was performed in only 3 patients, 2 (6.3%) with alterations, while colonoscopy had as its main finding an inflammatory process (37.5%) followed by the absence of an inflammatory process (31.3%). Regarding laboratory markers of indirect disease activity, there was a comparison between them, the initial ESR (Erythrocyte Sedimentation Rate) ranged from 3 to 120.0 mm/h, with a median of 42.5 mm/h, while C-Reactive Protein (CRP) ranged from 2.4 to 172.0 mg/L, with a median of 6.6 mg/L, fecal calprotectin (FC) ranged from 2.7 to 1750.0 μg/g, with a median of 165.0 μg/g. Conclusion: In this study, we found ulcerative colitis to be the most prevalent form of IBD, affecting women in the age group classified as young adults, with active disease and using medications indicated as a reference for the treatment of comorbidity. From the proposed study, we identified that the respondents follow the clinical epidemiological profile already presented in the literature from other regions of the country.Item A importância do processo ensino aprendizagem no módulo de interação em saúde na comunidade na percepção dos acadêmicos de medicina em uma Instituição de Ensino Superior no estado do Pará(Centro Universitário do Estado do Pará, 2025-05-28) Pessoa, Anna Karolina de Menezes Mangueira; Reis, Maryelly Damiana Oliveira de Carvalho dos; Pinto, Raquel Machado; Silva, Mariana do Socorro Quaresma; Santos, Roseane do Socorro Ferreira dos; http://lattes.cnpq.br/0319739561703154; Souza, Ivete Moura Seabra de; http://lattes.cnpq.br/5318491010793081; Matos, Haroldo José de; http://lattes.cnpq.br/9830983900880582In accordance with the teaching and learning evolution process, guided by the needs and changes experienced by society, as well as by the rules of the National Curricular Guidelines, medical schools have begun the process of inserting students into Basic Health Units since the first semesters of the course as a way of mediating their contact with the Unified Health System, aiming at approximation, recognition of limitations, advances and identification of the impact of this practice on the training of future general practitioners who will possibly work in the Unified Health System. The main objective of this study is to analyze the perception of medical students about the importance of the teaching and learning process in family and community medicine, since medical students are predominantly from a higher socioeconomic level and, therefore, many may not be familiar with the situational reality of a large part of the population to which they will provide care. Thus, methodologically, this is a cross-sectional, observational, descriptive study with quantitative components – continuous and discrete – and ordinal qualitative components with data collected from a specific form with responses using the Likert scale in the period from March to June 2024, which analyzed the perception of students, from the second to the eighth semesters, about the proximity of professional training to the principles and guidelines of the Unified Health System, the contribution to critical reflective training, with regard to home visits, territorialization and connection with the community and team, in addition to analyzing the students' view regarding the contribution of the module to their performance and safety in professional life. A total of 282 responses were analyzed, from a total of 560 students regularly enrolled between the second and eighth semesters of the course, whose predominant sex was female (64.2%). All coefficients were statistically significant and positive, reinforcing the importance of the MISC (Community Health Interaction Module) in aspects such as the recognition that the module promotes practical integration with the principles of the SUS, especially as the course progresses. It is concluded that the Community Health Interaction Module constitutes a crucial module in the training process of general practitioners, promoting practical integration with the principles of the Unified Health System and in the development of critical reflective skills, promoting a holistic medical practice and an aptitude for teamwork, indicating the relevance and positive impact on the education of medical students.Item Análise da percepção dos alunos de medicina sobre o método clínico centrado na pessoa: dimensão cuidar e compartilhar(Centro Universitário do Estado do Pará, 2025-05-28) Ricci, Débora Farias; Silva, Jullyana Nascimento; Santos, Marina Brito dos; Coelho, Érica Furtado Azevedo; Souza, Ivete Moura Seabra de; http://lattes.cnpq.br/5318491010793081; http://lattes.cnpq.br/5221363260090560; Romeiro, Janaína Cunha; http://lattes.cnpq.br/5894499630718939; Santos, Roseane do Socorro Ferreira dos; http://lattes.cnpq.br/0319739561703154This study aims to avaluate the perception of medical students about Patient-centered Clinical Method, highlighint the Sharing and Caring dimensons of the Patient-Practitioner Orientation Scale (PPOS), associating the average scores with the semesters from Centro Universitário do Estado do Pará (CESUPA). The research was held between February and December/2022 and was analysed between June/2023 and June 2024. It was approved by the Ethics Comittee according to the resolution n° 466/12 under the approval n° 5.635.569. The data collection happened through questionnaires applied in classrooms and on Google Forms. The results: the highest scores in the Sharing scale came from fourth, seventh and eighth semester. The fourth semester had the highest score, with 46 participants, a score of 4 and a standard deviation of 0,0293 - revealing a narrow variation between the students and a high consistency of data. In contrast, the eighth semester didn't fulfil the expectations, obtaining a similar score to the others despite the educational project indicating that at this point the students had already had classes dedicated to said theme, which may indicate dificulties to apply theoretical concepts in real life. On the Caring scale, the highest scores belonged to the first, sixth and fifth semesters, with the first semester being the highest; exposing the positive impact of the initial curriculum and the early exposure to patients. However, the third semester had lower results, probably due to the low number of participants - 13 students. The Caring scale had an average score of 4,4 and standard deviation of 0,088. Lastly, all semesters where graded as moderately patient-centered. In order to achieve better results, highly patient-centered, improvements like the enhancement in teaching and teacher training may be applied, as well as the development of new methodologies and revision of teaching practices.Item Perfil clínico-epidemiológico e abordagem terapêutica dos pacientes com síndromes nefrítica e nefrótica acompanhados no ambulatório de nefrologia pediátrica do Centro de Especialidades Médicas do CESUPA (CEMEC-CESUPA) entre 2019 e 2023(Centro Universitário do Estado do Pará, 2025-05-26) Costa, Francisco Pedro Silva da; Penha, Nelson Elias Abrahão da; Abrahão, Amanda Lobato Potiguar; http://lattes.cnpq.br/7501092836409389; Miranda, Marisa Eiró; http://lattes.cnpq.br/9869549838157176; Damasceno, Renata Trindade; http://lattes.cnpq.br/5784376787158358INTRODUCTION: Glomerular syndromes are among the main causes of chronic kidney disease in childhood, among the most prevalent are nephritic syndrome (post-streptococcal glomerulonephritis) and minimal change nephrotic syndrome. OBJECTIVE: To describe the clinical-epidemiological profile of cases of nephritic and nephrotic syndromes treated and monitored by the Pediatric Nephrology outpatient clinic of the CESUPA Medical Specialties Center (CEMEC-CESUPA). METHODOLOGY: This study used a questionnaire to collect information from 30 medical records of patients who were followed at the CEMEC pediatric nephrology outpatient clinic between January 2019 and December 2023. The data collected were on sex, skin color, age group, origin, diagnosis by ICD10, drug treatment, comorbidities, imaging tests performed, and renal biopsy. The data were tabulated and organized in graphs and tables. The study was observational, cross-sectional, and retrospective in terms of prevalence. RESULTS: The data revealed that most patients were male (74%), brown, between 4 and 7 years of age, and from the metropolitan region of Belém and Marajó Island. Most patients were initially diagnosed with nephritic syndrome (N009) (56.6%). However, the recommended drug treatment for patients with nephrotic syndrome was systemic corticosteroids. In addition, there were reports of patients with nephrotic syndrome who developed chronic kidney disease (13%), and renal biopsy was more prevalent in patients with this diagnosis. Most of the sample underwent kidney and urinary tract ultrasound (38.5%). CONCLUSION: It was observed that patients followed at CEMEC with a diagnosis of nephrotic syndrome tend to have a greater chance of complications when compared to those with nephritic syndrome, despite presenting a similar epidemiological profile for both pathologies. Further research is needed to determine the types of glomerulopathies and the main etiology of nephritic syndrome in these groups.Item Análise descritiva das internações e óbitos por diabetes mellitus nas macrorregiões brasileiras(Centro Universitário do Estado do Pará, 2025-05-27) Rabelo Junior, José Dorcele Paiva; Crisóstomo, Maria Laura Pereira; Cavalcante, Vitor Guilherme Araujo; Braga, Fábio Brito; Santos, Flávia Marques; http://lattes.cnpq.br/8601394323526613; http://lattes.cnpq.br/6301506178635436; Bastos, Fabíola de Arruda; http://lattes.cnpq.br/9386935778704228; Rocha, Vanessa Campos Couto da; http://lattes.cnpq.br/1897095774561517Introduction: Diabetes Mellitus (DM) is a chronic metabolic disorder characterized by an increase in glucose concentration in the bloodstream due to a deficiency in insulin secretion, action, or both. It is a disease associated with high rates of prevalence, morbidity, and mortality, especially in developing countries. In Brazil, more than 15.7 million adults live with the disease, which stands out due to the severity of its complications, and is therefore the sixth leading cause of death in the country. Objectives: to analyze the number of hospitalizations and deaths related to Diabetes Mellitus in Brazil over the last ten years, as well as their rates in each Brazilian region, aiming to understand the behavior of the disease during this period and identify possible associated determinants. Methodology: consists of an ecological study, of a retrospective and descriptive nature, with a quantitative approach. Secondary data on hospitalizations and deaths, obtained from the Hospital Information System - SIH (SIH/SUS) and related to DM (main diagnosis ICD-10 E10-E14), available at the SUS Information Technology Department (DATASUS), were analyzed. Results: A total of 1,477,043 hospitalizations for Diabetes Mellitus were recorded in the period, of which 65,353 resulted in death. Hospitalizations and deaths predominated in women aged 60 to 69 years treated in the southeast region. The average length of stay was 6.4 days and the total cost started at R$88,640,421.35 in 2013 and reached R$131,288,988.40 in 2023, with a total accumulated cost in the period of R$1,164,042,663.00. Conclusion: gender differences indicate a slight prevalence of hospitalizations and deaths due to diabetes in females. The following factors were found to be associated with a higher likelihood of hospitalization and death due to diabetes: advanced age, female gender, and living in the north, northeast, or southeast regions. Patients who fall into the extremes of age have longer hospital stays and higher mortality, indicating the need for specific approaches for these vulnerable populations and reinforcing the importance of targeted health policies, investments in diabetes prevention and management.Item Análise da utilização do simulador Body Interact™ no processo de aprendizagem no curso de medicina do CESUPA(Centro Universitário do Estado do Pará, 2025-05-26) Avertano-Rocha, Manoella Octavia Leopoldina Maria; Ferrari, Marina Figueiredo; Rodrigues, Natália Francisca Damasceno; Siqueira, Claudia Regina Dias; Carvalho, Ana Emília Vita; http://lattes.cnpq.br/1981562999898097; http://lattes.cnpq.br/6013946222269824; Guerreiro, Gustavo Pampolha; http://lattes.cnpq.br/7553169616952489; Andrade, Selma Parente Sousa; http://lattes.cnpq.br/4429392453942556Introduction: Realistic simulation is an innovative tool in medical education, allowing students to practice technical and behavioral skills in safe environments that replicate real scenarios. This methodology combines theory and practice, facilitating deep learning and the development of essential competencies to face complex situations. Simulation originated in fields such as the military and aviation, and in healthcare, it has evolved from the use of anatomical models to advanced simulators, such as Body Interact™, which offers virtual scenarios for clinical decision-making. This approach improves students’ preparation by offering controlled experiences that ensure safety for both future doctors and patients. Objective: To analyze the learning process of medical students before and after using the Body Interact™ simulator. Method: This is an observational, longitudinal study with pre- and post-intervention, using a quantitative data analysis approach. The study included 30 students regularly enrolled in the eighth semester, in the module “Professional Skills VIII (HP8)” of the medical course. In the demographic profile of the sample, females predominated (56.7%) and ages ranged from 18 to 25 years (66.7%). Only 13.3% of participants had prior contact with the virtual simulator. Data collection, after signing the informed consent form, occurred through questionnaires completed by undergraduates exposed to the Body Interact™ virtual simulator. Results: Based on the total frequency of responses, students showed improvement in knowledge and management of acute respiratory failure, with an increase in the percentage of correct answers ranging from 63.6% in the pre-test to 80% in the post-test, and from 61.2% to 65.2% in the debriefing stage. According to the Satisfaction and Self-confidence Scale, there was high agreement with the statements (above 50%). Conclusion: The use of the simulator significantly increased knowledge, even among those with no previous familiarity with the tool. The improvement in correct responses was significant in two items, with tendencies toward improvement in others. The simulation favored the organization and sequencing of actions, improved clinical reasoning, and enhanced the learning curve. Additionally, students showed greater self-confidence after the experience, confirming, therefore, the need to further study the topic.Item Perfil clínico epidemiológico de pacientes que realizaram testes respiratórios do hidrogênio em uma clínica privada de Belém(Centro Universitário do Estado do Pará, 2025-05-26) Moura, Marina de Araújo; Borges, Nicole Ribeiro; Sampaio, Regiane Miranda Arnund; Rodrigues, Ana Paula Guimaraes; http://lattes.cnpq.br/8714469084529838; http://lattes.cnpq.br/4904370452637372; Caldato, Cássio; http://lattes.cnpq.br/7526204330567369; Corrêa, Aida Lopes Sirotheau; http://lattes.cnpq.br/8922093304432676Introduction: Food intolerances (AIs) constitute a type of adverse reaction to foods, medicines or food additives, in which a non-immunological mechanism is involved, that is, a non-allergic hypersensitivity reaction. AIs have drawn attention due to the large quantity and variety of manifestations in the gastrointestinal tract, leading to difficulties in diagnostic identification and a decrease in the quality of life of these patients. Objectives: To describe the clinical epidemiological profile of patients who underwent hydrogen breathing tests at the Clínica Hepatonutri in Belém-PA. Methods: This is a research, with a descriptive and observational approach, cross-sectional and qualitative in nature, investigating patient data, through clinical data collection records carried out by analyzing physical and electronic medical records of patients treated at the service of Hepatonutri Clinic, from February 2022 to June 2024. Results: 63 patients were analyzed, the majority were female (80.95%). Regarding age, the predominance of 39.68% was adults between 40 and 59 years old. The main reasons for carrying out the tests were gas (28.6%), followed by diarrhea (25.4%) and abdominal distension (23.8%). The results point to a prevalence of 25.4% of food intolerance and 14.3% of Small Intestine Bacterial Overgrowth (SIBO) among the patients evaluated. During the examination, it was observed that 47.6% of patients experienced nausea followed by abdominal pain and gas (both 14.3%). The patients worked in a variety of professions, with the majority of patients being teachers (14.7%). Considering 34 patients who agreed to provide their epidemiological data, the majority (82.35%) had previous diagnoses, 26.47% had undergone previous surgeries. Regarding the use of medications regularly, 88.2% of patients used them. Ingestion of alcoholic beverages was reported by 26.47% of individuals. Regarding sleep, the majority of patients (67.64%) slept less than 8 hours per night. Half of the patients (50.0%) reported not practicing physical activity regularly. Conclusion: It was found that the epidemiological profile of the patients analyzed were women aged 40 to 59 years, in agreement with existing literature, which also highlights the prevalence of the diagnosis of IAs (fructose, lactose) or SIBO in women of this age. adult. The incidence of patients affected by AI's and SIBO in the Clinic sample analyzed showed that 26 of the 63 patients tested positive for these diseases.Item Perfil clínico e laboratorial dos pacientes com Diabetes Mellitus tipo 2 em uso dos Inibidores do Cotransportador Sódio- Glicose 2 (ISGLT2) no Centro de Especialidades Médicas do CESUPA (CEMEC)(Centro Universitário do Estado do Pará, 2025-05-27) Baidek, Vanessa Ferreira; Lobato, Vinícius Angelino Trindade; Bastos, Fabíola de Arruda; Lobato, Edienny Augusta Viana Santos; http://lattes.cnpq.br/8177968072238226; http://lattes.cnpq.br/9386935778704228; Santos, Flávia Marques; http://lattes.cnpq.br/8601394323526613; Rocha, Vanessa Campos Couto da; http://lattes.cnpq.br/1897095774561517Diabetes is a chronic systemic disease of great prevalence in Brazil that directly interferes with the quality of life of the population. Type 2 diabetes mellitus (DM2) is the most common type. The main complications in patients with DM2 are renal, cardiac and metabolic alterations. Aiming at the prevention of these complications, there are new therapeutic approaches that are safe and effective, such as sodium-glucose cotransporter 2 inhibitors (ISGLT2). Therefore, the study aimed to evaluate the clinical and laboratory profile of patients with DM2 using ISGLT2. For this purpose, a study was carried out, in which the methodology is based on a retrospective cross- sectional study, with the collection of data from the medical records of patients in the HIPERDIA, metabolism and nephrology outpatient clinics of the CESUPA Medical Specialties Center (CEMEC), from January to December 2023. The results evaluated demonstrate that of the 251 patients with DM2 evaluated at CEMEC, only 15% use the SGLT2 inhibitor. Furthermore, it was possible to evaluate the clinical profile related to the patients' existing comorbidities, presenting on average 78% of patients with hypertension and almost 99% with dyslipidemia. In addition, it was observed that there was no worsening of the parameters evaluated in laboratory tests such as glomerular filtration rate, blood glucose and glycated hemoglobin. Thus, this work demonstrates the impact of ISGLT2 on patients with DM2, through the analysis of the clinical and laboratory profile of these patients, contributing to better research development and prevention of systemic complications with the use of the SGLT2 Inhibitor.Item Análise do impacto da pandemia no atendimento do ambulatório de neurologia do Centro de Especialidades Médicas do CESUPA(Centro Universitário do Estado do Pará, 2024-06-03) Carvalho, Gabriel Santos de; Ribeiro, Renan Lazameth Carvalho; Valente, Daniele Azevedo; Neves, Dilma Costa de Oliveira; http://lattes.cnpq.br/7230812534416350; http://lattes.cnpq.br/3464693240863327; Souza, Aline Cristine Passos de; http://lattes.cnpq.br/5404002728453981; Santos Filho, Sérgio Antônio Batista dos; http://lattes.cnpq.br/7539226677465850Objective: To analyze the impact of the Covid-19 pandemic on care at the CEMEC neurology outpatient clinic and characterize the clinical-epidemiological profile of the population served pre-pandemic and during the pandemic, identifying patients with a history of COVID-19. Methods: This is an observational, cross-sectional, descriptive study, with a quantitative approach to data obtained from the records of a neurology outpatient clinic. Results: The annual average number of visits during the period was 78.5 per year and in the second period, this average increased to 157, that is, the annual average number of visits doubled during the pandemic period. A change in the age range of the profile was observed before and after the pandemic, with a prevalence of elderly people in current care. The main syndromic diagnoses being headache and epileptic syndrome, and the etiological diagnoses being epilepsy and migraine, with a significant increase in Parkinson's disease in the post-pandemic period. There were 138 cases of loss to follow-up, where during the pandemic period 3.6% of them were directly related to the course of the pandemic. Conclusion: In this way, this study is configured as an important tool to update the perception and direction of the neurology outpatient clinic, through the clinical epidemiological profile elucidated after the pandemic impact in this work, which allows sizing the new needs of this health service, as well as contributing as theoretical material for other health centers and a stimulating conduit for future scientific research.Item Perfil de pacientes diagnosticados com sarampo no estado do Pará na faixa etária de 0-14 anos no período de 2016 a 2021(Centro Universitário do Estado do Pará, 2024-06-03) Sá, Laís Miléo Gomes; Pires, Letícia Barreiros; Magno, Ismaelino Mauro Nunes; Silva, Silvana Cristina Rodrigues da; http://lattes.cnpq.br/6484463061528812; http://lattes.cnpq.br/3841081216551678; Oliveira, Kátia Soares de; http://lattes.cnpq.br/7676881940781206; Miranda, Marisa Eiró; http://lattes.cnpq.br/9869549838157176Measles is an exanthematous, highly contagious, acute and self-limited febrile illness. It has a viral etiology and mainly affects children between 6 months and 5 years old. It is among the causes of childhood morbimortality, and can be avoided through immunization. However, the reduction of the vaccination coverage in the state of Pará and the arrival of immigrants in the country contributed to the reintroduction of the previously eradicated pathology. This study aimed to identify the incidence of measles in children in the state of Pará in the period 2016-2021. This is an observational, descriptive, ecological and temporal study, carried out through consultations in the publicly available database of the Sistema de Informação de Agravos de Notificação (SINAN) and the Sistema de Informação do Programa Nacional de Imunização (SI- PNI), from the Departamento de Informática do Sistema Único de Saúde (DataSUS). It was observed that the highest incidence of Measles occurred in 2020, as well as the most affected age group was children under 1 year old, progressing, in most cases, with cure of the pathology. Furthermore, an increase in the incidence of measles in children aged between 0-14 years in the period analyzed (2016-2021) is directly related to a reduction in vaccination coverage in the state of Pará. It is concluded that measles is still a problem present in the state of Pará, therefore, high vaccination coverage (95%) must be achieved in order to obtain vaccine effectiveness and consequent eradication of the disease.Item O impacto da pandemia nas internações hospitalares por doenças do aparelho respiratório no estado do Pará(Centro Universitário do Estado do Pará, 2024-06-04) Nascimento, Laryssa Vieira do; Nunes, Leonardo Mendes Acatauassú; Matos, Haroldo José de; http://lattes.cnpq.br/9830983900880582; http://lattes.cnpq.br/3512764081076675; Neves, Dilma Costa de Oliveira; http://lattes.cnpq.br/7230812534416350; Tavares, Jessica Ramos; http://lattes.cnpq.br/1195489983106390The Covid-19 pandemic represented a period of instability for the health sector, leading to the loss of records of various pathologies that affected patients, including airway infections, which led to underreporting of these cases. Objective: To analyze the impact of the pandemic on hospitalizations for diseases of the respiratory system in the state of Pará from 2018 to 2022. Methodology: ecological, exploratory, temporal study, using data extracted from DATASUS in the Epidemiology and Morbidity tab and from the Mortality information, analyzing the variables of sex, age, year of hospitalization and year of death, considered in the list of morbidity of diseases and causes of death classified with alphanumeric code J00 to J99 (causes of morbidity and mortality due to diseases of the respiratory system ) established in ICD-10. Results: there was a decrease in records of hospitalizations for respiratory diseases, mainly in the North Region, which showed a 10.5% reduction in records between the pandemic and pre-pandemic period, which may be related to the difficulty in the region in maintaining a good database of disease notifications in health information systems. There was also a decrease in records of acute diseases such as pharyngitis and acute tonsillitis, bronchitis and bronchiolitis, mainly between 2019 and 2020. Pneumonia as the main cause of hospitalization for the population was a finding that was indifferent to sex and age. On the other hand, Influenza and asthma stood out due to the increase in records made between the pre- and post-pandemic periods, which may be related to the relaxation of health measures and social isolation, allowing greater interpersonal contact. In the analysis of data regarding sex and age, a close relationship can be observed between the increase in age and the recorded death rates, mainly among males, since this population is the most affected by comorbidities such as Diabetes Mellitus. and high blood pressure, factors that lead to a worse prognosis for diseases. Thus, it is notable that the pandemic had a direct impact on hospital admission records, with a direct correlation with the age and sex of patients when analyzing deaths from that same period.Item Avaliação de medicamentos potencialmente inapropriados e da polifarmácia em idosos de um centro de referência de Belém-Pará(Centro Universitário do Estado do Pará, 2024-06-03) Morelli, Luigi Pamponet Elias; Oliveira, Paula Valéria Alves de; Albuquerque, Mário Roberto Tavares Cardoso de; http://lattes.cnpq.br/3233617656287982; Costa, Tanise Nazaré Maia; http://lattes.cnpq.br/4471975369870057; Maués, Cristiane Ribeiro; http://lattes.cnpq.br/0584956998438639The excessive use of medications by the elderly not only brings potentially dangerous drug interactions but also susceptibility to adverse reactions, especially due to such interactions. In this context, it becomes necessary to discuss which medications are harmful to this target audience and their possible interactions, to identify possible less harmful alternatives. This work aimed to analyze the use of potentially inappropriate medications and the risks of iatrogenesis in elderly patients at CEMEC – Pará, according to Beers criteria. This is a cross-sectional and descriptive study, in which data collection was done using a questionnaire model developed by the researchers, in patients treated at the Elderly Health outpatient clinic of the Center for Medical Specialties of Cesupa (CEMEC), from January 2020 to March 2022. In the present study, 300 patient records were evaluated. Of these, the vast majority were women, aged between 70 and 79 years. The results regarding the quantity of medications used by the elderly revealed that the majority use more than five. Regarding the presence of heart disease or chronic illness justifying such use, it was revealed that most elderly patients have some comorbidity. Furthermore, regarding the presence of potentially dangerous drug interactions in this target population, there was no prevalence of these harmful interactions. In view of this, it is concluded that it is necessary to have knowledge of potentially inappropriate medications for the elderly, to avoid deleterious effects on their health. However, this research was positive, as it found efficacy in medication prescriptions with a reduction in drug interactions, providing safety and comfort to patients.Item Uso excessivo de analgésicos nos pacientes com cefaleia do ambulatório de neurologia do CEMEC - perfil clínico-epidemiológico(Centro Universitário do Estado do Pará, 2024-06-04) Correa, Ana Beatriz Rezende dos Santos; Leite, Bruna Verdelho; Pereira, Celice Cordeiro de Souza Bergh; Valente, Daniele Azevedo; http://lattes.cnpq.br/3464693240863327; http://lattes.cnpq.br/4509542877458910; Carvalho, Walther Augusto de; http://lattes.cnpq.br/0789028145294047; Castro, Yago Andrei Balieiro deHeadache is classified by the Global Burden of Disease study as the third most prevalent disorder worldwide, in addition to being the third leading cause of disability in both men and women under the age of 50. It has often been diagnosed and treated inappropriately, given the population's lack of knowledge about the different causes of the disease and the high frequency of self-medication with over-the-counter painkillers. Medication overuse headache is a secondary headache that usually occurs in patients suffering from primary headaches, worsening the intensity and frequency of attacks. This study aimed to identify the prevalence of excessive use of analgesics by patients diagnosed with headache, treated at the CEMEC neurology outpatient clinic. A cross-sectional, observational study was carried out with an analytical-descriptive approach. A higher prevalence of headache was noted in female patients, aged between 41-60 years, the main type being migraine. The most prevalent medication for pain control was Dipirone, which was significantly associated with excessive use of analgesics. Due to the lack of important information in the medical records, it was not possible to faithfully quantify the number of patients in the sample who were classified as overusing these medications. We concluded that a considerable portion of outpatient patients were overusing analgesics, predominantly female, and using Dipyrone, in addition to noticing a significant association between excessive use concomitantly with prophylactic treatment with Amitriptyline. Despite this, a lack of important information was observed in the medical records of patients with headache treated at the outpatient clinic, revealing the importance of creating a care record to be implemented in the institution, for better monitoring and outcome of these patients.Item Perfil epidemiológico das pacientes pós-menopausa acompanhadas em um ambulatório de climatério em Belém-PA(Centro Universitário do Estado do Pará, 2024-06-04) Guilhon, Ana Cláudia Reis; Maués, Gabriel Aranha Sousa; Maia, Matheus Rocha; Arêde, Mayana Batista Barros de; http://lattes.cnpq.br/3376521875715178; http://lattes.cnpq.br/6118052846256806Menopause is the permanent cessation of the menstrual cycle, reflecting the depletion of oocytes and the loss of gonadal steroids, so that this transition period in women's lives, most frequently experienced between 40 and 55 years of age, can be associated with great variability of symptoms. This study aimed to describe the epidemiological profile of postmenopausal patients followed at a climacteric outpatient clinic in the state of Pará and define the prevalence of hormonal treatment. A cross-sectional and descriptive study was carried out that included 73 postmenopausal women treated at the gynecology outpatient clinics of the Centro de Especialidades Médicas do CESUPA (CEMEC) from June 2018 to June 2023. The analysis took into account sociodemographic and historical data health, lifestyle habits and specific information about the use and experiences with Hormone Therapy. The majority of participating women identified themselves as mixed race (89%), living in urban areas (89%) and with an average age between 51 and 67 years (75.3%), highlighting a significant number of single women (53.4%). There was a tendency to be overweight (45.2%), with a low smoking profile (14%) and moderate alcohol consumption. Adherence to Hormone Therapy was influenced by a combination of factors, including age at onset of menopause and associated symptoms, with the majority starting treatment between 6 and 10 years after the appearance of the first symptoms. The study also revealed the importance of education and access to adequate information about menopause and the therapeutic options available, reflecting the need for more inclusive health policies adapted to the cultural and socioeconomic reality of women in Belém. It is concluded that there is a significant demand for more specialized health services sensitive to menopausal conditions, highlighting the need for public health strategies that address regional specificities and promote a better quality of life for postmenopausal women in the region.Item Perfil clínico-epidemiológico dos pacientes do ambulatório de nefrologia atendidos no Centro de Especialidades Médicas do CESUPA(Centro Universitário do Estado do Pará, 2024-06-03) Taboni, Angelo Ceccon Duarte; Dias, Denis Franco; Nunes, Lucas Lobato Acatauassu; Oliveira, Deborah de Alencar; http://lattes.cnpq.br/1121064921091959; http://lattes.cnpq.br/8764136693335864; Campos, Gabriela Oliveira; Baretta, Érica Moussallem Vasconcelos; http://lattes.cnpq.br/9677333497177047Introduction: Kidney diseases encompass a group of pathologies with high incidence in the population, among which this study will highlight five main conditions: Chronic Kidney Disease (CKD), Nephrolithiasis, Glomerulopathies, Diabetic Nephropathy, and Recurrent Urinary Tract Infections (UTIs). These conditions lead to significant clinical impacts, such as progressive renal function loss, alterations in other systems, need for hospitalizations and hemodialysis, resulting in a substantial impact on quality of life and healthcare costs. Therefore, this study aims to obtain the clinical-epidemiological profile of nephrological diseases among patients attending the Nephrology Outpatient Clinic. Objective: To determine the clinical-epidemiological profile of patients attending the Nephrology Outpatient Clinic at CEMEC (Medical Specialties Center of Cesupa) and to define strategies to improve the quality of healthcare for these outpatient patients. Methodology: This study will involve data collection from medical records of patients seen at the Nephrology Outpatient Clinic at CEMEC from January 2022 to June 2023. Data will be recorded by researchers using the questionnaire provided in Appendix D. After data collection, statistical software BioEstat and Spps 21 will be used for data analysis. The Chi-square test for goodness of fit will be used for single sample analysis, and the G-test will be used to compare independent samples. Results: This study analyzed 302 patients, mostly women (66.6%), predominantly over 50 years old (83.1%). The main diseases included Chronic Kidney Disease (CKD), Polycystic Kidney Disease, renal lithiasis, Urinary Tract Infections (UTIs), and Glomerulopathies. In CKD, stages G3, G4, and G5 were most common, with a high prevalence of albuminuria. The most commonly used medications were statins and Angiotensin II Receptor Blockers (ARBs). Anemia treatment included Erythropoietin and Iron Sulfate. Urinary Tract Infections (UTIs) were observed in 3.6% of patients, mainly with E. Coli. Nephrolithiasis was present in 8.9% of patients, mainly with calcium oxalate. The most frequent laboratory tests included Creatinine, Hemoglobin, and Vitamin D. Patients with Nephrolithiasis and Autosomal Dominant Polycystic Kidney Disease showed values within the normal range for many parameters. Conclusion: This study provides a comprehensive overview of the clinical-epidemiological landscape of nephrological patients treated at CEMEC. The information obtained has practical implications for the management and improvement of care for these patients, highlighting the need for continuous monitoring, early intervention, and an integrated approach to address the challenges associated with CKD and related conditions.Item Perfil epidemiológico de pacientes com diagnóstico de câncer de mama no Pará entre os anos 2020 a 2024(Centro Universitário do Estado do Pará, 2024-06-03) Motta, Camila Bentes; Bezerra, Luna Wanessa Vianna; Silva, Flávia Vasconcelos da; Barros, Luiz Fernando Lima; http://lattes.cnpq.br/5387620245589910; http://lattes.cnpq.br/9850385940493229; Ladeira, Érika Sampaio; http://lattes.cnpq.br/9523140163001182; Lima, Leila Suely Aviz; http://lattes.cnpq.br/9617281351879911Introduction: Introduction: Epidemiological studies play a crucial role in understanding cancer, a malignant disease that has been a significant cause throughout history. Cancer is characterized by the formation of neoplastic cells and the rapid dissemination capacity within the body. Such studies provide valuable information on the incidence, risk factors, clinical characteristics, and outcomes of breast cancer, enabling the development of effective strategies for prevention, diagnosis, and treatment. Objective: The objective of this study was to characterize the clinical and epidemiological profile of patients diagnosed with breast cancer between 2020 and 2024. Methodology: A descriptive study was carried out, based on data from DATASUS in order to identify the clinical profile-epidemiological analysis of patients diagnosed with breast cancer from 2020 to 2024. Results and discussion: During the period analyzed, breast cancer was more common in women, with 1,535 registered cases, compared to just 16 cases in men. The most prevalent age group for diagnosis was between 40 and 44 years old, with 206 cases, followed by the 45 to 49 years old group, with 189 cases. There was significant variation in incidence between cities, with Belém presenting the highest number of cases (756 records) and other cities with very low numbers, such as São Caetano de Odivelas and Santa Cruz do Arari, with only 3 cases each. Delivery of test results occurred within 0 to 10 days in most cases, although in some cases there were delays of more than 30 days. These results highlight the importance of awareness, early detection and improving the efficiency of healthcare processes related to breast cancer. Conclusion: The research provided valuable information about the clinical-epidemiological profile of breast cancer during the period analyzed. The results highlighted the higher incidence of the disease in women, the most affected age groups and significant regional variations. This information is essential to identify risk groups, target prevention and treatment strategies, and improve the efficiency of healthcare systems as breast cancer continues to be a challenge for the medical community, highlighting the need for continued research and innovative strategies to improve outcomes.Item Análise da tendência dos defeitos do fechamento do tubo neural em recém nascidos no estado do Pará antes e durante a pandemia(Centro Universitário do Estado do Pará, 2024-06-04) Souza, Camila Oliveira Ferreira de; Serique, Manuela Salame; Neves, Dilma Costa de Oliveira; http://lattes.cnpq.br/7230812534416350The analysis of the profile of live births with neural tube closure defects is a crucial field of medical research, as these anomalies pose a significant challenge to public health worldwide, involving both clinical and epidemiological, genetic, and social aspects. Objective: to analyze the anomalies of neural tube defects in the specific context of the state of Pará from 2018 to 2021. Methodology: observational, descriptive, exploratory temporal ecological study conducted through queries to the Live Birth Information System (SINASC) database, made available to the public by the Department of Health Informatics of the Unified Health System (Datasus), carried out from August to October 2023. Results: most cases of anencephaly occur in preterm babies, highlighting the importance of monitoring prematurity when assessing certain anomalies. The impact of the pandemic on the prevention of neural congenital malformations is also noteworthy. Before this period, there was a downward trend in cases, but in 2020 there was an increase in the number of cases, possibly associated with the disruption of prenatal care due to lockdown restrictions. The increase in diagnoses in 2020, compared to 2021, suggests that difficulties in conducting consultations and prenatal monitoring resulted in a higher number of live births with neural tube defects. The association between the pandemic and the increase in malformations, especially unspecified congenital hydrocephalus, highlights the need for strategies to mitigate impacts on prevention practices during global health crises. The relationship between gestational age and the prevalence of anencephaly emphasizes the importance of considering gestational time when investigating specific malformations, highlighting a significant association with prematurity. Conclusion: adequate prenatal care is necessary, as well as public policies that promote appropriate monitoring from the early stages of gestation.Item Perfil epidemiológico dos nascimentos no Brasil a partir das declarações de nascidos-vivos entre 2006 e 2015(Centro Universitário do Estado do Pará, 2019) Paula, Fillipe Augusto Moura de; Damasceno, Ana Cláudia Alves; http://lattes.cnpq.br/6202464010989232Introduction: Birth and birth are transformative events in the lives of women and babies, and most often, they are not at risk. Brazil went from a high-fertility regime to a low-fertility and long-term internal and external regime to improve the quality of care for the newborn and to reduce maternal and infant mortality. Objective: To analyze the socio-epidemiological profile of births in Brazil from the birth-to-child report by Sinasc in DATASUS, corresponding to the period from January 2006 to December 2015. Results: About 29.2 million live births were born between 2006 and 2015. The year of 2015 registered the highest rate and year of 2010 the lowest. As for seasonality, the March-April-May quarter had the highest rates, with 26.8% of total births and the lowest October-November-December quarter (23.6%). There was an increase in the proportion of births of mothers aged 30 years or older, from 24.53% to 32.79%, and a reduction in the proportion of those aged less than 20 years, from 24.48% to 18.14%. There was an increase in the birth rate where mothers performed prenatal care with 7 or more consultations, from 54.54% to 66.49%. About 2% of the births were of multiple gestation, with maintenance of this percentage in the period. The incidence of low birth weight in the period was 2.45 million births. Cesarean section was the type of delivery in 52.07% of births, with an increase of 10.46 percentage points of this way of delivery in the period. 2.6 million premature infants (8.95% of the total live births) were born, with a rate increase from 6.61% to 10.83% in the period evaluated. Apgar score higher than 7 (good vitality) occurred in 82.27% of the total live births, and 93.39% presented the same score in the 5th minute of life. The incidence of births with an Apgar score lower than 8 in the first minute was higher in preterm (32.82%) compared to the term and post term (15.8% and 19.9%, respectively). Conclusion: The Live Birth Information System (Sinasc) is a good and timely source of information about births in Brazil. It is possible to trace the profile of births, having as a basic document the Declaration of Live Birth (DNV). The results obtained are very important for the knowledge of many variables that may help in the future the construction of strategies aimed at improving the Brazilian Health system.Item Perfil epidemiológico das pacientes com lesões precursoras e câncer do colo de útero atendidas em um Centro de Especialidades Médicas(Centro Universitário do Estado do Pará, 2019) Silva, Giovanna Gomes e; Furtado, Lidia Lacerda; Campos, Ana Carla Araujo; http://lattes.cnpq.br/4066530269438763Introduction: Carcinoma of the uterine cervix is the fourth most incident cancer in women in Brazil, in 2018, was expected 16.340 new cases of carcinoma of the uterine cervix in Brazil. At the region North, including Pará State, this cancer is the most incident at the female population, just behind non-melanoma skin cancer, where were diagnosed 820 new cases in 2016. The profile of women that develop this kind of cancer, stand out early age at first sexual intercourse, multiplicity of partners, history of sexually transmitted infections, use of the oral contraceptives, multiparity, early pregnancy and tabagism. Objectives: To describe epidemiological profile of patients with uterine cervix cancer treated at a specialized medical center. Methods: A descriptive and retrospective study was performed. Data were collected from medical records of patients diagnosed with uterine cervix cancer or precursor lesions from 2015 to 2018, sociodemographic information and main characteristics that are considered as risk factors for the development of the disease were collected. Results: The average age of the patients was 41,5 years, most were divorced, illiterate, multiparous, the first sexual intercourse occurred between 8 and 24 years and had altered cytopathological exams and colposcopy. Conclusion: The data analyzed allowed to characterize the epidemiological profile of patients with carcinoma of the uterine cervix and its precursor lesions in the population studied. These data have relevance in the implementation of public actions for patients with similar profiles, so that screening and early diagnosis can be performed.