Navegando por Assunto "Hepatopatias"

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A importância da ultrassonografia no diagnóstico da doença hepática gordurosa não alcóolica
(Centro Universitário do Estado do Pará, 2020) Mendes Netto, Ataíde José; Rocha, Everton Roberto de Castro; Silva, Flavio Tavares Freire da; http://lattes.cnpq.br/1386374444157946; Rodrigues, Ana Paula Guimaraes; http://lattes.cnpq.br/8714469084529838; Caldato, Cassio; http://lattes.cnpq.br/7526204330567369
Introduction: Non-alcoholic fatty liver disease is considered the most common cause of liver disease in the world, being also a hepatic manifestation of the metabolic syndrome. In this context, the objective of this study was to determine the prevalence of non-alcoholic hepatic steatosis diagnosed by ultrasound in patients seen at an outpatient clinic of a Higher Education Institution in the city of Belém - PA. Methodology: Descriptive, documentary and cross-sectional study with a quantitative approach carried out with 115 patients who underwent abdominal ultrasound at the Centro de Especialidades Médicas of Centro Universitário do Pará in 2019. The association between metabolic syndrome and non-alcoholic liver steatosis was assessed by the test Fisher's exact, considering p≤0.05 statistically significant. Results: Most patients were female (71.3%), aged between 50 and 69 years old (53%), brown (90.4%) and married or in a stable relationship (41.7%). There was a high prevalence of obese patients (43.5%) with arterial hypertension (69.6%) and diabetics (32.2%). The prevalence of non-alcoholic hepatic steatosis was 72.2%, statistically associated with the presence of metabolic syndrome (p = 0.0001), where 89.1% of patients who had this syndrome had non-alcoholic hepatic steatosis. Conclusion: There was a high prevalence of non-alcoholic hepatic steatosis among patients, associated with metabolic syndrome. Therefore, it is emphasized that the early diagnosis of hepatic steatosis helps to monitor individuals with a chance of developing metabolic syndrome. In addition, ultrasonography proved to be a sensitive and effective test for the detection of hepatic steatosis, given the high prevalence of this disorder in the population studied.
Hipotireoidismo causando ascite e elevação de marcador tumoral/CA 125: um relato de caso
(Centro Universitário do Estado do Pará, 2021) Silva, Igor Martins Gonçalves; Mesquita, Ricardo Paulo Pereira; Moraes Junior, Rudival Faial de; http://lattes.cnpq.br/5666162407518627
Introduction: Ascites is a common condition and is closely associated with liver, neoplastic and infectious diseases. In cases of ascites associated with elevation of the CA-125 tumor marker, hypothyroidism should be investigated because when it is decompensated, it can cause ascites. Treatment is through hormone replacement with levoritoxin. Objective: to report the case of ascites caused by hypothyroidism. Case report: a 45-year-old female patient was referred to the hepatology service for etiological elucidation of ascites. During investigation, liver, neoplastic and infectious diseases were ruled out, and TSH >500UI/ml was observed with refractory ascites. After the introduction of levothyroxine, the clinical picture of ascites resolved. Conclusion: This case is remarkable because ascites caused by hypothyroidism associated with elevation of tumor marker CA-125 is a rare clinical condition. Due to the uniqueness and complexity of the clinical picture, hospitalization and extensive medical investigation were necessary to first exclude the causes of greater incidence and severity. Therefore, hypothyroidism should be investigated when other more common etiologies do not explain the condition.
Internação de pacientes por doença hepática no Brasil de 2009 a 2018
(Centro Universitário do Estado do Pará, 2020) Neves, Anie Rebecca Oliveira; Santana, Carolina Iris Pereira de; Lins, Nara Alves de Almeida; http://lattes.cnpq.br/7967734262982303
Liver diseases are a major cause of hospitalization worldwide, and has been on the rise over the last few decades, mainly due to chronic liver diseases such as alcohol, non-alcoholic fat, cirrhosis and chronic hepatitis by the C virus, which, without the appropriate assistance, increase the hospital costs of assistance for these patients, creating the possibility of an unfavorable evolution of these, who may need a liver transplant. Objective: to define the average hospitalization time for liver disease patients by region of Brazil, from 2009 to 2018, correlating with the expenses related to this permanence and their respective mortality rate. Method: ecological, quantitative and descriptive methodology, based on data, publicly available through SIH/ DATASUS. Results: there was a downward trend in the number of hospitalizations for liver diseases in 2018. Even though it is not statistically significant, the reduction is mainly due to alcoholic liver diseases. It was also noted that other liver diseases lead the number of hospitalizations in Brazil, mainly affecting males in the 40-59 age group, with a downward trend of 20-39 years. Regarding the average stay, in Brazil, the average is 8.5 days for alcoholic diseases and 8.8 days for non-alcoholic ones, with less stay in the South region (7.4 days) and more days in the North and Northeast (9.3 days). With regard to the amount paid for the treatment of liver diseases, there was a 58,4% increase in the 10 years studied. The highest hospital mortality rate is mainly due to alcoholic disease, with the southeast region having the highest mortality rate; and to the north, the smallest. In addition, mortality from general liver disease in Brazil, by region, was caused mainly by alcoholic disease, in the 40-59 age group, and liver fibrosis and cirrhosis for those over 60, predominantly in men. Regarding liver transplants, the number of cases has been growing slowly over the period studied, with the largest increase in expenses observed in the period from 2011 to 2014 due to the implementation of new transplant centers, in which the southeast region was the one that had the largest number of these procedures. Conclusion: It was noted that the amount paid for hospital services for the treatment of liver disease patients increased by 58,4% in the decade studied, but the average hospital stay remained practically constant, as well as the hospital mortality rate by region, per year, did not have a significant change, showing that even when spending more, the service is unable to maintain its efficiency and effectiveness.
Perfil epidemiológico dos principais achados ecográficos associados a afecções hepatobiliares em pacientes atendidos em um Centro de Especialidades Médicas
(Centro Universitário do Estado do Pará, 2021) Rodrigues, Ana Carolina Conde; Moraes, Hanna Camila Alencar de; Silva, Flavio Tavares Freire da; http://lattes.cnpq.br/1386374444157946
Background: Abdominal ultrasound is a sensitive and relevant exam in the diagnosis of alteration in the liver, gallbladder, extra and intrahepatic bile ducts, which contributes to the diagnosis of hepatobiliary disorders and to the determination of possible surgical difficulties. Objective: Define the epidemiological profile of the main echographic findings associated with hepatobiliary disorders at a medical specialties center in Belém, PA, Brazil. Methodology: Cross-sectional, statistical and descriptive study, with quantitative approach, based on medical records analysis of patients who were under medical care at the ultrasound outpatient clinic of the Centro de Especialidades Médicas – CEMEC of the Centro Universitário do Estado Pará – CESUPA and underwent abdominal ultrasound between August and December 2019. Age, sex and main echographic findings were analyzed. The BioEstat 5.5 software was used for statistical analysis and the tables and graphs were executed in Microsoft Word and Excel software. p < 0,05 was adopted as significance level. Results: A total of 205 patients were evaluated (133 women and 72 men). There were 122 altered exams (59.5%), 83 female (70.5%) and 36 male (29.5%). The conditions most frequently described were mild hepatic steatosis (37.1%), followed by moderate hepatic steatosis (10.7%) and cholelithiasis (9.3%) The median age patient’s was 51 years. Conclusion: Abdominal ultrasound is a reliable method in the diagnosis of hepatobiliary disorders due to its high sensitivity and specificity regarding the pathologies that affect this tract. Its performance helps in the diagnosis and monitoring of patients so that they do not progress with complications and do not undergo surgical procedures late.