Hipotireoidismo causando ascite e elevação de marcador tumoral/CA 125: um relato de caso

Abstract

Introduction: Ascites is a common condition and is closely associated with liver, neoplastic and infectious diseases. In cases of ascites associated with elevation of the CA-125 tumor marker, hypothyroidism should be investigated because when it is decompensated, it can cause ascites. Treatment is through hormone replacement with levoritoxin. Objective: to report the case of ascites caused by hypothyroidism. Case report: a 45-year-old female patient was referred to the hepatology service for etiological elucidation of ascites. During investigation, liver, neoplastic and infectious diseases were ruled out, and TSH >500UI/ml was observed with refractory ascites. After the introduction of levothyroxine, the clinical picture of ascites resolved. Conclusion: This case is remarkable because ascites caused by hypothyroidism associated with elevation of tumor marker CA-125 is a rare clinical condition. Due to the uniqueness and complexity of the clinical picture, hospitalization and extensive medical investigation were necessary to first exclude the causes of greater incidence and severity. Therefore, hypothyroidism should be investigated when other more common etiologies do not explain the condition.