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Aspectos clínicos e histopatológicos do lúpus eritematoso cutâneo registrados em serviço de referência do estado do Pará no período de 2010 a 2017
(Centro Universitário do Estado do Pará, 2019) Lima, Luis Felipe Silva; Gouvêa, Rebecca Ribeiro; Bittencourt, Maraya de Jesus Semblano; Amin, Gabriela Athayde; http://lattes.cnpq.br/8604283847300465; http://lattes.cnpq.br/6566823528602319
INTRODUCTION: Systemic Lupus erythematosus (SLE) is an autoimmune and multifactorial disease characterized by a chronic inflammatory process resulting from changes in immune regulation due to the production of autoantibodies against various cellular constituents. The skin is one of the target organs most affected by the disease, and genetic, hormonal and environmental factors interact and interfere with the development of skin disease. The cutaneous manifestations can be divided into specific and nonspecific, according to their clinical and histological characteristics, and the specific ones can be found in the skin in three ways: chronic (CCLE) ; Subacute (SCLE) and Acute (ACLE). It presents genetic, autoimmune, hormonal and environmental factors as pathogenic substrates, and its clinical and laboratory characteristics help the diagnosis, which can be confirmed by histopathological study. OBJECTIVES: This study aims to elucidate the histopathological changes that occur in the LECC and its subtypes, correlating the disorders analyzed in the slides with the clinical manifestations presented by the patient. MATERIAL AND METHODS: This was a cross-sectional, retrospective and descriptive study conducted at the dermatology service of the Federal University of Pará through the analysis of medical records in which the disease was histologically confirmed. RESULTS: We analyzed epidemiological and clinical data from a group of 55 patients with Cutaneous lupus erythematosus (CLE) . The average age at disease onset was 42 years. There was a predominance of females (80% of cases). 64% of the cases affected the face, and 51% were disseminated or generalized in the skin (with lesions also below the neck). There was a predominance of erythema and peeling (87% and 47% of cases), followed by atrophy (42%). The most affected phototype was IV in 61.8% of cases. 33% of the cases were CCLE, followed by ACLE in 13 patients (24%) and SCLE in four patients (7%). The most frequent dermatological lesion was erythema (87%), followed by scaling, infiltration and atrophy. 29% of patients had positive antinuclear factor. In the epidermis it was observed that all cases presented vacuolar alteration, 64% of patients presented basal thickening and 58% atrophy. In the dermis, all patients presented lymphocytes in the infiltrate and 87% presented mucin in the connective interstices. CONCLUSION: Understanding the changes that appear at the microscopic level is of paramount importance for understanding the course of the disease and, thus, enabling the elaboration of an appropriate therapeutic approach. The medical professional plays a fundamental role in the management of patients with Cutaneous lupus erythematosus, and their duty is to understand all its universality for a satisfactory clinical follow-up and the prevention of possible injuries. Although not a common disease, its chronicity leads to the accumulation of cases in clinical outpatient clinics. In addition, although progress is good in most cases, delayed initiation of treatment can lead to disfiguring scars.
Aspectos epidemiológicos dos óbitos de crianças por afogamento nas regiões brasileiras
(Centro Universitário do Estado do Pará, 2019) Rezende, Maíra dos Santos da Mata; Gonçalves, Vívian Danielle Bastos da Silva; Neves, Dilma Costa de Oliveira; http://lattes.cnpq.br/7230812534416350
Introduction: Drowning is the leading cause of unintentional death in children, among external causes, and the one that has the greatest family, social and economic impact. It is a public health problem, in which prevention is the main tool. Objectives: Describing the epidemiological profile of children from 0 to 11 years old who were victims of drowning and accidental submersion that evolved to death in the Brazilian regions and capitals from 2010 to 2017. Methodology: Ecological study whose data were collected from the Mortality Information System (SIM) provided by the IT Department of the Unified Health System (Datasus). The study variables were: age, sex, race/color, year of death (2010 to 2017), place of death, region of occurrence and the primary cause of death classified in ICD-10, with alpha numeric code W65 to W74. The variables were grouped by Brazilian Regions. Results: Drowning as the primary cause of death in children in Brazil represented 19.3% (6,296) of all deaths from external causes, with the highest proportion (32.8%) observed in the Northern Region. The highest proportion of drowning deaths occurred in the state capitals was observed in the Midwest Region (25.1%), followed by the North Region (19.3%). It was observed that deaths from drowning children tend to increase in the Midwest and South regions and to decrease in the North, Northeast and Southeast regions. The predominant age group of deaths was between 0 and 2 years of age (2,405), mainly in the North, Midwest, South and Southeast. In the Northeast, there was superiority in the age group from 6 to 11 years (919), with the highest absolute number of drowning deaths in children. There was a predominance in males (4,337) in all Brazilian regions, with higher occurrence in the Northeast. Brown race/color was predominant in all regions except the Southern region. The mortality rate was higher in children aged from 0 to 2 years (163) in all regions. The main day of the week for all regions was Sunday, with a predominance of afternoon time. As for the place of occurrence, excluding the unspecified place of occurrence (615), the drowning of children in natural waters (422) stood out in all regions, followed by residence, for the North and Northeast regions and pool in the Center regions. West, South and Southeast. In the North and Northeast regions, the most frequent age range in natural waters is from 6 to 11 years and in residence from 0 to 2 years. While in the South, Southeast and Midwest, the occurrence of drowning in natural waters predominated, with the most frequent age range between 6 and 11 years, followed by swimming pool, aged between 0 and 2 years. Conclusion: We emphasize the importance of the results obtained for the creation of drowning prevention strategies in children, contributing to the improvement of the quality of life of families and society as a whole.
Associação entre o pertencimento a grupos de risco para COVID-19 e o estado emocional autorreferido de cidadãos brasileiros durante a pandemia de 2020-2021: um estudo transversal
(Centro Universitário do Estado do Pará, 2021) Sizo, Marcele de Pinna; Fukushima, Vanessa Iukari; Teixeira, Cláudio Eduardo Corrêa; http://lattes.cnpq.br/7448998858430931
Introduction: In early 2020, the world began to experience impacts of different magnitudes at different levels and activities of human society, due to the occurrence of the pandemic of a new coronavirus (SARS-CoV-2), which causes a systemic disease, now recognized as COVID-19. In this context, the acquisition and interpretation of epidemiological data, many of a nature never worked on before, became essential for preventive decision-making and for containing the spread of the disease, as well as for clarifying the real impacts of the pandemic. Objective: To investigate whether there is a correlation between being in a risk group for severe COVID-19 and having some impairment in emotional status related to pandemics. Methodology: This study is characterized as observational, cross-sectional, exploratory. Data were obtained from a questionnaire distributed by social networks to all Brazilian states from April 2020. Among more than 60,000 respondents, 45,025 informed if they are part of any risk group for serious disease and if they present any it harms your emotional state. Correlation between these datasets were carried out using linear autocorrelograms. All data were organized, cleaned and worked using the statistical computer program R. Results: The results show that, in general, there is no significant correlation between being from a risk group and having an impaired emotional state, regardless of whether the citizen is an adult or elderly, female, male or other. Conclusion: We conclude that the impact on mental health generally related to the pandemic must be associated with factors other than the presence of risk factors for serious illness.
Avaliação clínica da gravidade em pacientes portadores de Doença Pulmonar Obstrutiva Crônica (DPOC) atendidos no CEMEC – CESUPA
(Centro Universitário do Estado do Pará, 2019-11-20) Ayres, Layse Melo Menici; Navarro, Stéphanie de Windson Cruz; Pinheiro, Marilia de Fátima Silva; http://lattes.cnpq.br/2037104893893669; Monteiro, José Tadeu Colares; http://lattes.cnpq.br/7627103187307808; Santos, Roberta Kahwage; http://lattes.cnpq.br/2527080199033009
Introduction: Chronic Obstructive Pulmonary Disease - COPD is a common, preventable and irreversible condition, defined as a syndrome characterized by chronic airflow limitation, evolving with destruction of the pulmonary parenchyma. Smoking is the main cause and respiratory signs and symptoms characterize it. The FEV1 / FVC ratio < 0.7 after bronchodilator administration is used for diagnosis and is classified by the Global Initiative for Chronic Obstructive Lung Disease (GOLD) in ABCD for clinical severity and 1234 for degree of obstruction. Objectives: General: To evaluate the severity of COPD in patients followed at CEMEC. Specifics: 1) Classify patients according to severity in groups A, B, C and D. 2) Characterize the relationship of severity with the variables gender, age, BMI, smoking load, oximetry and medications in use of the patients studied. 3) Characterize the relationship of variables with the mMRC scales and exacerbating profile. 4) Compare FEV1 among patients classified by symptomatology. 5) Compare the spirometric profile of exacerbating and non-exacerbating patients. Methodology: The medical records were searched through ICD J44 in CEMEC where 25 of them fit the delimited profile and their variables were collected and analyzed. Results: A higher prevalence was found in groups C and D (66.66%), aged 55 to 78 years, with the highest mean BMI in group B (30.9 kg / m2) and most females (12). / 21). Post-bronchodilator FEV1 was found to be higher in less symptomatic patients (59.4 ± 24.1). 61.11% of the patients had a smoking load > 20 packs / year, most of them also exacerbating (13/21). Regarding the therapy applied to the GOLD ABCD groups (n = 17), it was found that 12 were on monotherapy, five in combination and only one had no scheme. Conclusion: A significant number of patients who did not really fit the ICD J44 were observed; Of the 25 patients, only 21 had sufficient data for ABCD classification, among them, most were in groups C and D. The female gender was more prevalent, as well as the patients with the highest smoking load; Among the most symptomatic, there was a higher obstructive degree, and it was possible to trace the severity profile of these patients treated at the service.
Avaliação do conhecimento de pais e responsáveis sobre a síndrome do bebê sacudido
(Centro Universitário do Estado do Pará, 2021) Rosário, Isabelle Souza do; Neves, Dilma Costa de Oliveira; Oliveira, Kátia Soares de; http://lattes.cnpq.br/7676881940781206; http://lattes.cnpq.br/7230812534416350
Introduction: Shaken Baby Syndrome (SBS) is a form of physical abuse that occurs when the child is strongly agitated resulting in the formation of subdural or subarachnoid hematoma, diffuse cerebral edema and retinal hemorrhages, with serious consequences for child development. Objectives: To assess the knowledge of parents and caregivers who attend the Cesupa Medical Specialties Center (CEMEC) about Shaken Baby Syndrome (SBS). Methodology: An observational, cross-sectional and analytical study, carried out by applying a questionnaire on the level of knowledge of parents and caregivers about SBS. Results: The study shows that 90% of respondents think it is wrong to shake a child under 6 months of age. Among the consequences related to the act of shaking a baby, 96% indicate that the baby can get sick and 70% that the baby can vomit. It was found that 39.6% think that reflux can be a disease associated with the act of shaking a baby and 33.3% believe that it would be physical and mental problems. The age group from 20 to 29 years was the most prevalent (54%) among respondents, with a predominance of females (88%). About 76% declare themselves brown, 48% have a monthly income of 1 to 2 minimum wages and 48% declare themselves “housewives”, 84% do not use alcohol or other drugs and 68% have high school education. Mothers or fathers of babies represent 90% of respondents. The predominant age group among babies was between 9 and 12 months (72%). Among respondents, 50% agree that caring for a baby can be tiring and stressful. Regarding the reason for the baby's crying, 86% of the participants think that the baby cries because he is hungry, 72% because he is in pain and 70% because he is sick. The main strategy used to calm a baby when crying was play (54%). Conclusion: The low knowledge of the severity of shaking, compared to the high knowledge that shaking is bad for the baby's health, may be related to the name of the syndrome. This fact reaffirms the need for educational interventions in health services in order to contribute to the increase in parental knowledge and the consequent prevention of this injury.
Avaliação do risco cardiovascular em pacientes com lúpus eritematoso sistêmico atendidos no CEMEC
(Centro Universitário do Estado do Pará, 2019-05-20) Borborema, Augusto Lopes Pereira de; Santos, Felipy Chaves dos; Cristino, Sônia Conde; Rodrigues, Fabíola Brasil Barbosa; http://lattes.cnpq.br/2425897539868497; http://lattes.cnpq.br/7942684022038270; Ohashi, Claudia Barros; http://lattes.cnpq.br/0889116450004563; Costa, Alberto Freire Sampaio; http://lattes.cnpq.br/8830564785408868
Introduction: Systemic Lupus Erythematosus - SLE is a disease of autoimmune origin with a large number of clinical and laboratory manifestations. The pathophysiological nature of lupus involves both chronic and atherosclerotic inflammatory processes, which gives pathology an important role in the genesis of changes related to the cardiovascular system. In this context, it is essential to use the Framingham score in an attempt to estimate the cardiovascular risk in lupus patients and the interaction with traditional and non-traditional risk factors. Objectives: General: To evaluate cardiovascular risk in patients with Systemic Lupus Erythematosus in follow-up at CEMEC. Specific: To establish the prevalence of cardiovascular risk factors in SLE patients followed at CEMEC; 3) To characterize the epidemiological profile of patients with SLE treated at CEMEC; 4) Describe the characteristics of patients with SLE treated at CEMEC and relate it to cardiovascular risk. Methods: A research protocol was developed in which patient information is fundamental to the research: age, sex, time of illness, smoking, systolic blood pressure, total cholesterol, HDL, diabetes, medications in use and type of SLE. The search for data was based on the analysis of medical records of patients with SLE treated at CEMEC. Subsequently, these data were applied to the Framingham score. Results: It was observed that of the 68 patients who met the inclusion and exclusion criteria, 88.2% were female, 33.8% were in the age group below 30 years of age and 44.1% (n = 30) present a disease time between 6 and 10 years. Cutaneous involvement was the most prevalent, with 88.2% of cases. Regarding cardiovascular risk, 94.1% of the patients presented low risk, 1.5% medium risk and 4.4% high risk. The Immunossupressor / Immunomodulator class is part of the treatment of 92.6% of the patients. Conclusion: The study concludes that the Framingham score was not able to correctly identify cardiovascular risk in SLE patients.
Impacto clínico e prognóstico das modificações no sistema TNM do American Joint Committee For Cancer oitava edição em pacientes com câncer de mama
(Centro Universitário do Estado do Pará, 2019) Bohne, Mariana Rocha; Khayat, Yasmin de Farias; Pereira, Cynthia Mara Brito Lins; Khayat, André Salim; http://lattes.cnpq.br/6305099258051586; http://lattes.cnpq.br/3186657130674078
Introduction: Breast cancer is in fifth place as the cause of cancer death in the world population. In Brazil, this neoplasm is a first in the female public, without considering non-melanoma skin cancer. However, with the objective of conducting early research on the biological causes of breast cancer, there was a great reduction in mortality rates and greater survival in patients with metastatic disease. The American Joint Committee on Cancer (AJCC) is a state cancer system that enables disease progression. The AJCC instituted its history form based on anatomical information of the primary tumor ("T"), regional lymph nodes ("N") and metastases ("M"). Biological factors, tumor grade, estrogen receptor (ER) positivity, HER2 and progesterone receptor (PR), were included in the eighth edition of the manual, implemented in 2018. Aim: This work aimed to analyze the impact generated by the update of the TNM / AJCC staging system (eighth edition) and to elucidate the importance of including the biological factors and other modifications of the new system for a better medical approach. Method: A retrospective, analytical, cross-sectional, and documentary study of a qualitative approach in which patients with breast cancer were submitted to Ophir Loyola Hospital in 2018, having undergone the cancer staging of the TNM of the American Joint Committee on Cancer (AJCC) seventh edition, so that it could be reclassified according to the prognostic status of the eighth edition of this manual. Socio-demographic data, hormonal and reproductive histories, risk factors related to cancer, anatomopathological characteristics, biological factors and molecular subtype of the tumors were considered. Conclusion: Changes in the stage of the breast cancer patients evaluated after the reclassification with the eighth edition of the TNM / AJCC system were found, so that there was a positive impact of this system on the prognostic targeting, generating a better therapeutic selection.
Perfil clínico epidemiológico de pacientes cadastrados no Hiperdia – PA: série histórica de 10 anos
(Centro Universitário do Estado do Pará, 2021) Monteiro, Fernanda Tereza Silva; Silva, Rafaela Abadessa da; Neves, José Joaquim de Oliveira; http://lattes.cnpq.br/9075377277147026
Introduction: Brazil has a high prevalence of people with Diabetes Mellitus and Systemic Arterial Hypertension, with significant growth in recent years, with well-known risk factors, in addition to serious complications, therefore deserving appropriate interventions. Objectives: To characterize the clinical and epidemiological profile of patients enrolled in the Hiperdia program in the State of Pará from 2003 to 2012. Methodology: The Study is a 10-year (2003 to 2012) historical series of a descriptive and quantitative type, with a survey of the number of cases of patients with concomitant hypertension and DM, using data available from the public domain by DATASUS. The data are detailed by the municipalities of the State of Pará, more specifically by their regional situations (Araguaia, Baixo Amazonas, Carajás, Lake Tucuruí, Metropolitana I, II and III Caetés, Tapajós, Tocantins, Xingu and Marajó I and II). Results: The study shows that about 65% of the registered patients were female and the age group where there was the highest record was 55 to 59 years old. About 77% of the patients registered in the program were not smokers, 57% were not sedentary and 58% were not overweight. It was found that 93% of the participants did not have AMI, 95% of the patients did not have coronary heart disease, 12% had a stroke and 90% of those registered did not have kidney disease. Approximately 5% of the patients had a diabetic foot condition and the elderly, 3% had to undergo amputation.36% of the patients registered in the program were part of the Metropolitan Health Region I. Conclusion: Among those registered, 65% were female; The predominant age group was 55 to 59 years old; 57% practice physical activity and 23% were smokers; 58% were overweight; absence of AMI in 93% and coronary disease in 95%; stroke observed in 12% of cases and foot diabetic in 5% (since 3 years, have needed amputation), renal complications in 10% of cases and the regional health that registered the most was Metropolitano I.
Perfil epidemiológico de tuberculose extrapulmonar na região metropolitana de Belém
(Centro Universitário do Estado do Pará, 2021) Maia, Juliane Tayse Ribeiro; Sá, Lorenna Luciano; Souza, Rhomero Salvyo Assef; Neves, José Joaquim de Oliveira; http://lattes.cnpq.br/9075377277147026; http://lattes.cnpq.br/5327528039741804
Introduction: Tuberculosis is one of the diseases with the greatest impact on morbidity and mortality in Brazil, with a high number of new cases every year. It is an airborne disease caused by species that make up the Mycobacterium tuberculosis complex. The most frequent extrapulmonary affections are pleural, lymph node, urogenital and meningoencephalic. Objectives: To analyze the epidemiological profile of new cases of extrapulmonary tuberculosis in the Metropolitan Region of Belém between 2016-2020. Methodology: The research was descriptive, with an analytical and cross-sectional study carried out through the analysis of secondary basic data, indicators and notifications of extrapulmonary tuberculosis made available at the Informatics Department of the Brazilian Unified Health System (DATASUS) - Disease Information System of Notification (SINAN). In the period from 2016 to 2020. Results: Belém is responsible for 82.36% of cases between 2016-2020, equivalent to 1,168 of the population detected with extrapulmonary tuberculosis. In the regions of Marituba and Santa Bárbara do Pará, there has been an upward trend in the last year, with the municipality of Marituba showing the highest detection rates of extrapulmonary tuberculosis per 100,000 inhabitants. It is noted that in all years between 2016-2020 women had the highest rates, with almost 17% in 2019. However, men also had the highest rate in 2019, with 12%. It is also noticed that the rates between 2019-2020 are declining, but there is still a rising municipality in the male population. It is evident that the Pleural form is the most prevalent with 48% of cases, followed by the Peripheral Ganglional form, responsible for 22%. The year 2019 has the highest number of cases of patients immunosuppressed by HIV, with 23.95% of the total cases. Conclusion: In the Metropolitan Region, incidence rates continue to rise, although the capital has reduced the number of cases in the last year.
Perfil metabólico comparativo entre pacientes com obesidade infantil do CEMEC e pacientes eutróficos do ambulatório geral de pediatria do Preventório Santa Terezinha
(Centro Universitário do Estado do Pará, 2020) Oliveira, Carlos Henrique Novelino de; Oliveira, Emanuella Lemos Chaves de; Rocha, Mônica Souza Filho Moura; Neves, José Joaquim de Oliveira; http://lattes.cnpq.br/9075377277147026; http://lattes.cnpq.br/1302412321438738
Introduction: Brazil has a high prevalence of overweight and obesity, with a significant growth of children with obesity between 6 and 18 years old mainly. Among the consequences, there is a change in the lipid profile, hypertension and early diabetes. This promotes considerable complications in adulthood, such as Metabolic Syndrome. Obesity is identified as one of the main risk factors for altering the metabolic profile in children, hence the importance of establishing epidemiological profiles that facilitate interventions. Objective: Describe the comparative metabolic profile between patients with childhood obesity at CEMEC and eutrophic patients at the general pediatric outpatient clinic, Belém-PA. Methodology: Cross-sectional study of a descriptive character with a quantitative approach. Based on medical records from the childhood obesity outpatient clinic of CEMEC-CESUPA and the General Pediatric Outpatient Clinic of Preventório Santa Terezinha, dated from 2017 to 2019. A chi-square likelihood ratio test was performed, with a significance level adopted for the analysis of the variables: Fasting glycemia, total cholesterol, LDL, HDL, triglycerides in eutrophic and obese men and women aged 5 to 10 years and 10 to 15 years. Results: Children with obesity compared to eutrophic children had a higher blood glucose level of 6.73 mg / dL, a higher cholesterol level of 14.20 mg / dL, a lower HDL level of -3.17 mg / dL, the highest LDL at 11.25 mg / dL and the highest triglyceride level at 36.90 ml / dL in relation to eutrophic. In children with abnormalities, obese men, 10 to 15 years of age, stand out. Conclusion: Most children, obese and eutrophic, had normality in almost all variables except for triglycerides. It was also noticed that, despite the majority being normal, the obese had average values higher than the eutrophic in all variables, except in HDL where they had lower levels.
Prevalência de fatores de risco em pacientes com alteração no processamento auditivo central atendidos no Centro de Especialidades Médicas do CESUPA
(Centro Universitário do Estado do Pará, 2021) Correa, Leticia Larrat; Coelho, Tammyle Reis; Força, Mariana Tótola; http://lattes.cnpq.br/4000323182108455
Introduction: Central auditory processing (CAP) is the physiological mechanism for conducting auditory information from the cochlea, a peripheral sensory organ, to the upper auditory centers ¹. Knowledge of the risk factors associated with central auditory processing disorder (CPD) is important for clinical suspicion, reducing the negative impact on language and cognition in these patients. Among these risk factors are dyslexia, attention deficit hyperactivity disorder (ADHD), autism spectrum disorder (ASD), neonatal hypoxia, congenital hypothyroidism (CH), secretory otitis media in the first 5 years of life, hospitalization of baby in ICU for 48 hours or more, syndromes, family history, facial blood anomalies and congenital diseases ⁴-¹¹. Objectives: To analyze the prevalence of risk factors in patients with alterations in the central auditory processing of the otolaryngology service of CEMEC. Methodology: The study is observational, cross-sectional and quantitative, using medical records of patients who have alterations in central auditory processing in the otorhinolaryngology outpatient at Clinic of the Medical Specialties Center of CESUPA. Results: Nineteen patients with central auditory processing disorders were included in the study, and only two (10.5%) were female. The age at diagnosis was mainly six to ten years, in 47.4% of cases. The prevalence of risk factors found in the sample. Ten reported non-risk-determining patients (52.6%), seven had ADHD (36.8%) and at a lower frequency, two had ASD and neonatal anoxia and dyslexia were reported in one patient each. It is observed that learning difficulties were the most reported pre-diagnostic complaint, in 63.2% of cases, followed by speech delay and inattention (36.8%).Conclusion: It appears that the vast majority of patients found were male, with greater frequency in the age group of 6 to 10 years at diagnosis. The most common risk factors were ADHD, followed by ASD, neonatal anoxia and dyslexia.
Prevalência de hipertensão arterial sistêmica entre os docentes do curso de medicina do Centro Universitário do Estado do Pará
(Centro Universitário do Estado do Pará, 2019) Reis, Ana Catarina de Souza Carvalho; Azevedo, Silvia Karinny Brito Calandrini de; Rocha, Vanessa Campos Couto da; Mota, Diandro Marinho; http://lattes.cnpq.br/7979118007430529; http://lattes.cnpq.br/1897095774561517
Systemic arterial hypertension (SAH) is a multifactorial disease, in which the individual presents progressive and continuously elevated blood pressure values in relation to the criteria established by VII Diretriz Brasileira de Hipertensão Arterial from Brazilian Society of Cardiology (PA  140/90). Such syndrome is associated to innumerable modifiable and non-modifiable risk factors. This clinical condition, in turn, is an important risk factor for cardiac and cerebral complications. Objective: to identify the prevalence of arterial hypertension among professors of the school of medicine at Centro Universitário do Estado do Pará; during the year of 2018. Method: Cross-sectional descriptive epidemiological study based on data collected obtained by questionnaires, pressure and anthropometric values measurements taken from School Medical professors from June to September (third term of 2018). The populational sample encompasses 77 professors. A percentage of (45; 54.45%) out of a total of 77 was found to be women. Results: Data analysis revealed a hypertension prevalence of 29.9% over populational sample. The same prevalence hits 37.5 % among men and 24, 44% among women. As for hypertensive individuals, the average age of arterial hypertension is a range from 39 to 48. A percentage of 52.18 out of a total of 23 hypertensive individuals was found to be unaware of hypertension condition. Among the individuals who already knew to be hypertensive, 45.45% had controlled blood pressure values. Conclusion: The prevalence of SAH was 29.9%. From hypertensive patients, 52.2% were male. Among the hypertensive professors, 52. 18% of the condition had no previous knowledge of the disease. Regarding those who knew to be hypertensive, only 45.45% used antihypertensive medication regularly and 54. 55% did not present controlled blood pressure values. As for the analyzed risk factors among those 77 professors, the highest prevalence group associated to overweight hits (46.7%). Central obesity hits (50.6%). Alcoholic drink intake reached (61%).Stressed group hits (54.5%). Low physical activity levels or sedentary lifestyle hits (49.3%). And those with SAH (77.9%) and AIM (46.7%) familiar history.
Relação de polimorfismos genéticos específicos como fatores de risco para o desenvolvimento de Malformações Arteriovenosas (MAVs) cerebrais: uma revisão sistemática
(Centro Universitário do Estado do Pará, 2019) Santos, Leonardo Magalhães; Farias, Valter Fernando Rodrigues; Paschoal Júnior, Fernando Mendes; Paschoal, Eric Homero Albuquerque; http://lattes.cnpq.br/1593548343125421; http://lattes.cnpq.br/0171195401629428
Arteriovenous Malformations (AVMs) of the brain are vascular lesions that shunt arterial blood directly into a low-resistance system of draining veins without an intervening normal capillary bed. Among the main clinical manifestations (which contribute greatly to the cases of death of this pathology), hemorrhage and seizures are prominent. The pathophysiology of this condition is still poorly understood, but the role of proinflammatory cytokines and genes responsible for these cytokines and cerebral angiogenesis in this process is recognized. The present work aimed to identify the relationship of specific genetic polymorphisms as risk factors for the development of Cerebral Arteriovenous Malformations (AVMs). A systematic review of the literature was performed, using the PRISMA Statement as the research protocol, in the MedLine databse. The terms / descriptors in Health Sciences, in the English language, included in the research of the title were: genetic polymorphism, arteriovenous malformation, single nucleotide polymorphism, genetic linkage, brain arteriovenous malformation, hemorrhage, seizures and headache. Case-control studies were included in this study, where, in the research methodology, the genetic tests used to identify the polymorphism and the presence of AVM in image examination were established. The extraction of articles was done by two authors independently. In all, 208 articles were found, of which only 11 fulfilled the inclusion criteria of this research. The most affected age group was in the range between 35 and 40 years. AVMs, in general, presented with a mean size of 3 to 6 cm. Of the analyzed polymorphisms, all had a direct relationship between having the polymorphism and being an MAV (each with its statistical frequency). And, of the more present clinical manifestations, the hemorrhage was highlighted. It is concluded that more studies should be listed to highlight the role of genetic polymorphisms in this process, in order to improve the therapeutic arsenal to lead this pathology and the prognosis of patients.