Ganglioneuroblastoma em adolescente: incidentaloma adrenal pós-COVID 19 - um relato de caso raro

Abstract

Introduction: Ganglioneuroblastoma (GNB) is a rare malignant tumor of the adrenal gland. Symptoms depend on the location of the mass effect or the existence of the metastasis. As for the diagnosis, tumors of the neural crest in adults are rare and there is a difficulty in differentiating them only by imaging exams. Objective: To report a case of rare adrenal pathology with an incidence of less than five cases per 1,000,000 children, discovered after Computed Tomography of the Chest performed as a protocol of the COVID-19 disease, making a comparison with the cases reported in the world literature. Method: This is a rare case report study associated with a review of articles published in the world literature on the topic of ganglioneuroblastoma in adults. Case report: We present the case of a previously healthy 18-year-old man was diagnosed with Covid-19 and performed a chest Computed Tomography (CT) scan that showed an incidentaloma described as an oval formation in the right retroperitoneum, anterior to the adrenal. An endocrinologist evaluated the patient with a complete normal physical examination, as well as a hormonal laboratory that proved to be normal. Specialist indicated diagnostic excision, a procedure performed laparoscopically. The pathological examination consisted of a right adrenal and a nodular mass. With diagnosis of GNB intermixed subtype. Conclusion: The patient in the reported case does not fit the disease presentation pattern. Few data are available on the diagnosis and treatment of adults with GNB, making clear the importance of case report publications on the subject.