Trabalho de Conclusão de Curso - TCC

URI Permanente para esta coleçãohttps://repositorio.cesupa.br/handle/prefix/41

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Coinfecção HIV/Sífilis em homens vivendo com HIV em centro de referência de assistência em AIDS em Belém
(Centro Universitário do Estado do Pará, 2020) Gaia, Gabriel Nogueira; Santos, Jéssica Almeida; Brígido, Helena Andrade Zeferino; http://lattes.cnpq.br/6780493949155060
Introduction: Coinfection between HIV and Treponema pallidum has a synergistic action, characterized by both the increased transmission of HIV and the atypical evolution of treponemal infection. Therefore it is necessary to demonstrate the rates and relationship of syphilis coinfection and HIV / Aids. Objectives: To analyze the prevalence and factors related to syphilis coinfection and HIV / aids in the city of Belém-PA, as well as to describe sociodemographic and behavioral characteristics and to identify the factors associated with human immunodeficiency virus (HIV) co-infection and acquired syphilis cases. Methods: Cross-sectional, prospective and descriptive qualitative study that consisted of the application of a questionnaire prepared by the researchers. We interviewed and followed 127 patients followed in a reference institution in Infectious Diseases and Sexually Transmitted Infections (STI) in 2018-2019 in the State of Pará. Results: The total number of patients interviewed (127) was properly distributed after analyzing the data and their variables. There was a predominance of patients between 30-34 years (24.4%) and 25-29 years (18.1%). When asked which race / color, 81 (63.8%) identified as brown. Approximately half of the patients, 63 (49.6%), when analyzed for exposure category, identified themselves as homosexuals, while the other half was divided between heterosexuals 41 (32.03%) and bisexuals. 23 (18.1%). Regarding the diagnosis and development of aids, 64 (50.4%) had developed Aids, which represents more than half of the number of patients analyzed. When asked about the highest level of education obtained so far 51 (40.2%) have completed high school. When analyzing the data on the distribution of the diagnosis and treatment of syphilis already performed, it was observed that 44 (34.6%) patients at some point in their life had already been treated for syphilis, the main scheme used was benzathine penicillin G, corresponding to 40 (90.9%) of the total. In addition, 18 (14.2%) patients reported having a current or past sexual partner with syphilis. Of the 127 patients who participated in the interview, when evaluated in the laboratory for the results of FTA-ABs, 23 (76.7%) patients were reactive. Finally, when evaluated for the immunological and virological state of the disease, in laboratory terms, considering CD4 + values and Viral Load, there was a significant proportion of CD4 +> 350 cells / mL and Undetectable viral load. Of the total, 94 (80.3%) had such lymphocyte count> 350 cells / mL. Regarding the Viral Load result, 97 (82.9%) presented undetectable viral load, ie, less than 50 copies / ml. Conclusion: The study demonstrates the high prevalence of syphilis and HIV / Aids coinfection among patients treated in the city of Belém, as well as identifies the unequal distribution of the disease, taking into account socio-demographic aspects such as age, race, exposure category and schooling. The results may support a possible reorganization of care and medical service regarding the development and progression of such diseases.
Perfil epidemiológico de pacientes HIV positivos atendidos no ambulatório de infectologia de um Centro de Especialidades Médicas em Belém, Pará
(Centro Universitário do Estado do Pará, 2021) Castro, Charles Fabrício Ferreira; Lima, Michel Martins Braga; Gomes, Patrick Abdala Fonseca; Neves, José Joaquim de Oliveira; http://lattes.cnpq.br/9075377277147026; http://lattes.cnpq.br/6060836341247026
Introduction: The Acquired Immunodeficiency Syndrome is a set of signs and symptoms related to the infection of the human organism by the Human Immunodeficiency Virus (HIV), historically associated with groups such as homosexual men, hemophiliacs and users of injectable drugs, undergoes an important process of epidemiological transition, progressively increasing its incidence in heterosexuals, women and low-income people. In addition, the North region, especially the state of Pará, presents an important increase in the number of HIV / aids cases. over the past 10 years. Objective: To analyze the epidemiological profile of patients with HIV / aids treated at the Infectious Diseases Clinic of the Cesupa Medical Specialties Center (CEMEC) in Belém, Pará, from 2012 to 2020. Materials and methods: This is an epidemiological study , descriptive and cross-sectional, in which data from medical records of people living with HIV and aids treated at the Infectious Diseases Clinic of the Center for Medical Specialties of Cesupa, in Belém, were analyzed. Results: 91 medical records were analyzed. Of these, 57 patients were men (62.6%) and 34 were women (37.4%). The average age was 41.8 ± 12.6 years, with a predominance (80.2%) of mixed race. The majority of female infected were heterosexual (96.7%), while the majority of male infected were homo or bisexual (60.8%). Also, most of the infected female sex lived in a stable relationship (57.6%, married or in a stable relationship), while the majority (75%) of the infected male sex lived alone (single, divorced or widowed). The main route of infection was sexual (97.1%), 70.6% were still being treated at the center studied and the majority (72%) had an undetectable viral load and CD4 +> 350 (72.2%). 41.8% did not have co-infections and 54.9% did not have comorbidities. Conclusion: It appears that the profile of the sample studied was composed mainly of young adults, without a steady partner, browns, with a predominance of men, of heterosexual orientation, where the sexual route was the most frequent source of infection. Of the total, the majority had an undetectable viral load, CD4 + count> 350, using Antiretroviral Therapy (ART) and with the majority not reporting co-infections or associated comorbidities.
Situação epidemiológica do HIV/AIDS no estado do Pará no período de 2010-2019
(Centro Universitário do Estado do Pará, 2021) Marques, Konnery Kazelly Marinho; Angnes, Paulo Vitor Cavalcante; Teixeira, Cláudio Eduardo Corrêa; http://lattes.cnpq.br/7448998858430931
Introduction: The HIV infection courses with a wide spectrum of clinical presentations from its acute to the chronic phase, being considered a global public health problem with a burden of more than 33 million deaths, considering its relevance at a global level, the implications brought due to HIV infection and aids and the factors that favor its recurrence, it is important to investigate the epidemiology of HIV/aids and the factors that influence it, evaluating the epidemiological indicators in the state of Para from January 2010 to December 2019, in order to provide pertinent information for the application of better public policies to the population studied. Objectives: To analyze the epidemiological situation of patients with HIV/aids through epidemiological indicators in the state of Para from January 2010 to December 2019. Methodology: This is an observational, descriptive and quantitative study, based on an exploratory document analysis (secondary data) using the HIV/aids epidemiological bulletin (2020) as the main source. The sample consisted of patients diagnosed with HIV/aids in the state of Para, its capital Belem, the North region and in the national sphere, analyzing the detection rate and the mortality coefficient from January 2010 to December 2019, using as analysis variables sex, ethnicity/race/color, education and exposure category. Results: The aids detection rate in Brazil, in the period between 2010 and 2019, decreased by 20%, however the North region, the state of Para and the city of Belem showed growth in their rates of respectively 20%, 37% and 43 %. The crude aids mortality coefficient shows that in the period from 2010 to 2019 there was a decrease of 21.87% in cases of death in Brazil, while there is an increase in the North, Para and Belem, respectively, of 8.47%, 26.15% and 20.43%. Conclusion: The present study evidenced a growing trend in the detection rate in the North region, mainly due to the numbers in the state of Para and its capital Belem, contrary to the trend observed in Brazil. One of the factors involved may be related to problems in data transfer between the municipal, state and national spheres.

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