Navegando por Assunto "Mucosite oral"

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Efeitos comparativos da fotobiomodulação utilizando laser de baixa intensidade ou diodo emissor de luz na mucosite oral em pacientes pediátricos que receberam altas doses de metroextrato: estudo prospectivo, randomizado e controlado
(Centro Universitário do Estado do Pará, 2019) Ota, Tâmara Melo Nunes; Guimarães, Douglas Magno; http://lattes.cnpq.br/6439076195866691; Tuji, Fabrício Mesquita; http://lattes.cnpq.br/8122254353290848; Ribeiro, André Luis Ribeiro; http://lattes.cnpq.br/9899528924354409
Purpose: The objective of this study was to compare the efficacy of photobiomodulation using low-level laser therapy (LLLT) or light emitting diode therapy (LEDT) devices for the prevention of oral mucositis in pediatric patients diagnosed with acute lymphoblastic leukemia undergoing chemotherapy with high doses of methotrexate (MTX). Methods: 80 patients were randomly divided into two groups: LLLT and LEDT. Both protocols were applied with the same energy and radiant exposure. The protocols started in the beginning of high doses MTX and finished when the patients were discharged from the hospital or there was oral mucositis resolution. The oral mucositis was assessed during each session in accordance to the World Health Organization (WHO) score. The patients self-assessed pain was scored on a visual analog scale (VAS). Results: the incidence of oral mucositis was similar to LLLT and LEDT, 10% and 12,5% respectively. Both groups required the same number of days to reach score of zero for mucositis and pain (p > 0.05) and there was no significant difference in mean VAS between the groups. Conclusions: These findings suggest that LEDT has similar effects to LLLT and can be a low cost and easy application tool to avoid and treat oral mucositis.
Fotobiomodulação com led e parâmetros laboratoriais no contexto de mucosite oral após altas doses de metroextrato em pacientes infanto-juvenis
(Centro Universitário do Estado do Pará, 2021-04-16) Ferreira, Isabella Melo Brito; Guimarães, Douglas Magno; http://lattes.cnpq.br/6439076195866691; Tuji, Fabrício Mesquita; http://lattes.cnpq.br/8122254353290848; Lima, Rafael Rodrigues; http://lattes.cnpq.br/3512648574555468
Cancer is a major cause of death among children and adolescents; and chemotherapy is the most used modality. Among the oral complications developed during chemotherapy treatment, oral mucositis (OM) is the most observed and its treatment is extremely necessary. Photobiomodulation is capable of exerting an analgesic and healing effect on the patient, where it becomes a viable alternative for prevention and treatment in all stages of OM. Objective: to stipulate the effectiveness of LED in the prevention of OM during the treatment of children and adolescents. Method: retrospective analysis of 123 medical records of patients undergoing a photodynamic therapy protocol with LED for treatment and / or prevention of the main oral manifestations related to chemotherapy using the SALUX software (Porto Alegre, RS, Brazil). Results: The LED phototherapy protocol for the treatment and / or prevention of oral mucositis related to chemotherapy was applied in all 118 patients, where 28 patients (23.8%) evolved with OM, of which 10 (35.7% ) were classified as grade 1; 12 (42.9%) classified as grade 2 and 6 (21.4%) as grade 3, with no cases classified as grade 4. It was observed that patients without the prophylactic protocol with LED develop OM 35 times more than patients who received the protocol (p <0.0001). Patients who developed OM presented changes in blood indexes, mainly in hemoglobin, hematocrit, TGP and TGO. Conclusion: photodynamic therapy is effective in preventing OM in juvenile children undergoing chemotherapy, with laboratory values of hemoglobin, urea, TGO and TGP and clinical picture of febrile neutropenia as risk factors for the development of oral mucositis.