Navegando por Assunto "Gastrite"

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Associação entre epigastralgia e o consumo de açaí em uma amostra de população com alta prevalência de câncer gástrico
(Centro Universitário do Estado do Pará, 2022) Ghammachi, Thiago de Oliveira; Teixeira, Cláudio Eduardo Corrêa; http://lattes.cnpq.br/7448998858430931
Historically, the State of Pará has a high incidence of gastric cancer. In 2018-2019, according to the National Cancer Institute, gastric cancer was the second most frequent in men (12.35/100,000 inhabitants) and the fifth most frequent in women (5.34/100,000 inhabitants in the North Region). Often, the diet of the local population is pointed out as an important factor for the occurrence of epigastric pain, gastritis and gastric cancer. It was hypothesized that the excessive consumption of some elements of this cuisine may contribute to an excess of stomach acidity, increasing the activity of the H+/K+ pump in the parietal cell membranes of the stomach, which extracts K+ from the lumen and pumps H+ into it, acidifying -O. Therefore, the following research intends to investigate the association between the consumption of açaí, often consumed with cassava flour, both rich in K+, and the manifestation of epigastralgia. Thus, data from a center and thirty-three (133) patients were used in this crosssectional study, data from 133 patients treated at the Hepatology and Gastroenterology Clinic of CESUPA were used through a cross-sectional study. Data analysis was performed using the statistical computing program R (www.r-project.org), calculating the prevalence ratio (PR, ± 95% confidence interval [ICI95% ]), in addition to analyzing proportions with Fisher's exact test (alpha = 0.05). This work was approved by the Ethics Committee (Opinion 5,429,013). Obtaining as a result that patients who consume açaí were more likely to present epigastric pain as a clinical symptom (PR = 3.692 [CI95%: 1.226-10.14], p = 0.0247). Concluding that the consumption of açaí may have a prone effect to epigastric pain. However, further investigations need to be carried out to better clarify this finding.
Avaliação dos resultados dos exames de endoscopia digestiva alta realizadas em um hospital do município de Belém-PA no ano de 2019
(Centro Universitário do Estado do Pará, 2022-11-08) Domingues, Eduardo de Pinho; Rymsza, Gabriel Pacheco; Caldato, Cássio; http://lattes.cnpq.br/7526204330567369; Sampaio, Regiane Miranda Arnund; http://lattes.cnpq.br/4904370452637372; Guimarães, Ana Paula Araujo; http://lattes.cnpq.br/8106253183599673
Introduction: An Esophagogastroduodenoscopy (EGD) is a very important exam nowadays, since it is the most used exam for diagnosis and monitoring of some pathologies. With the increasing presence of gastrointestinal symptoms in the entire population, largely due to risky lifestyle habits for the development of diseases, this test has been increasingly used. In addition, hygiene conditions also directly influence Helicobacter Pylori (HP) infection, which is one of the main risk factors for the development of gastric mucosal diseases. The most prevalent pathologies in the population undergoing this examination are inflammation of each segment of the digestive tract, such as esophagitis, gastritis and bulboduodenitis . In addition to these, we can also find more serious lesions, such as Barrett's Esophagus and neoplasms of each segment. Finally, endoscopies can also be therapeutic, performing minimally invasive interventions such as gastrostomies, polypectomies and ligation of esophageal varices. Objective: To identify the most common findings found in EGD in patients at the Guadalupe Hospital, in Belém-PA. Methodology: This work is an observational, analytical and cross-sectional study, through the analysis of reports of esophagogastroduodenoscopy (EGD) performed in patients at the Guadalupe Hospital in Belém-PA, during one year (2019), identifying the main findings of these tests. Results: 1358 patients were included in the study. Most patients (883 or 65%) were female. 478 of them (35.2%) were aged between 60 and 79 years and the avarege age was 54 years. Almost all subjects (1350 or 99.4%) had gastric alterations. 5.7% (77 subjects) had duodenal changes. 36.2% of the subjects had esophageal alterations. 0.8% (11 individuals) had suggestive neoplasms test. 50.4% (684 people) had two or more endoscopic findings. From the 1358 patients submitted to the examination, only 25 (1.8%) of them did not present any alteration in the endoscopy. Among the patients with gastric alterations, 990 (73.3%) had enanthematous antral gastritis . In duodenal alterations, 71.4% of the individuals had erosive bulboduodenitis . The majority (446 or 90.8%) of esophageal findings were erosive esophagitis. As for the suggestive neoplasms findings, 72.7% of them were found in the stomach. The association between sex, age group and the presence of alterations was verified. There was a significant association between sex and presence of alterations (p=0.027): in males, 99.4% had alterations, this proportion being higher when compared to that expected by the statistical test. Conclusion: The performance of a quality EGD is essential for accurate diagnoses, as well as its proper indication. The present study statistically disagreed with the international rates of abnormal tests, perhaps due to the adequate request for tests, according to the guidelines of the country in which this study was carried out. The main pathologies found were those of inflammatory origin, however, considerable numbers of pre-malignant and malignant lesions were also seen, such as Barrett's Esophagus and neoplasms, respectively. This exam is even more important in these last mentioned pathologies, because early diagnosis allows a better prognosis. It is also possible to correlate these main findings with the population's life habits, which play a relevant role in the emergence of these diseases, however, the study did not possess these data from the patients who underwent the exams, which may contribute to future studies that may use this information.
Tratamento de gastrite associada à infecção por Helicobacter Pylori no Centro de Especialidades Médicas do CESUPA
(Centro Universitário do Estado do Pará, 2019) Guerra, Andressa da Silva; Custódio, Sávio Sérgio Ferreira; Valente, Tárik Olívar de Nunes; http://lattes.cnpq.br/9516550105434600
Objective: To describe the epidemiological profile and treatment of patients with gastritis associated with Helicobacter pylori infection treated at CESUPA's Medical Specialties Center (CEMEC). Method: The cross-sectional descriptive study was carried out at the Center of Medical Specialties (CEMEC) of the University Center of Pará (CESUPA), from August 2018 to February 2019, where 352 medical records of patients regularly enrolled in the CEMEC’s Gastroenterology service during the first half of 2016 until the first half of 2018 were analyzed. Data collection was done according to the Data Collection Research Protocol. Results: In this series, the majority of the patients were female (80%). This study revealed that the majority of patients were concentrated in the age group between 51 and 70 years. Triple therapy with amoxicillin, clarithromycin, and pantoprazole was the most widely used regimen in this study, considering that all patients who tested positive for H. pylori infection were treated. It was observed that about 6% of patients started treatment with levofloxacin, clarithromycin and proton pump inhibitor (PPI). The vast majority of patients did not require retreatment (76.7%), but those who needed it were treated with levofloxacin, amoxicillin and proton pump inhibitor. Conclusion: There was a predominance of gastritis associated with Helicobacter pylori infection in women and in the population between 51 and 70 years. Regarding therapy of choice, the regimen with amoxicillin, clarithromycin and pantoprazole was the most used. The need for retreatment was identified in 23.3% of the patients, with levofloxacin, clarithromycin and PPI being the choice for these patients (66.7%).