Navegando por Assunto "Cefaleia"

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Avaliação do manejo preventivo de pacientes com enxaqueca no ambulatório de neurologia do Centro de Especialidades do CESUPA no período de 2014-2018: um estudo retrospectivo
(Centro Universitário do Estado do Pará, 2019) Costa Neto, Antônio da Luz; Gomes, Fernando Bispo; Sefer, Celina Cláudia Israel; http://lattes.cnpq.br/0218316102057635
Introduction: Migraine is one of the most prevalent causes of pain in Brazil and globally, being incapacitating when severe. They are primary headaches and are classified for their etiology in migraine with aura and without aura. Treatment is performed according to the specificity of migraine. Thus, it is imperative that there be a knowledge of the medical conduct on this subject, so that it cannot only diagnose and treat, but also adequately guide patients with migraine in outpatient services. Objective: To evaluate the preventive management of patients with migraine at the CEMEC-CESUPA Outpatient Neurology in the period 2014-2018. Methodology: Retrospective study of 961 patient charts from the CEMEC-CESUPA Neurology Outpatient Clinic. 52 charts followed the exclusion and inclusion criteria established for this research. The sample characterization information was compiled in databases prepared in Microsoft Office Excel® 2016 software; adopting a significance level α < 0.05. Results: There was a predominance of females (88.46%), with a prevalence of patients with migraine without aura (55.8%) compared to aura (44.2%). The most evident age at onset of migraine was between 19 and 30 years (39.1%). Among the patients analyzed, 88.5% reported severe pain and only 5.8% moderate pain, and there were no subjects who reported poor pain or absence of pain. Migraine attacks usually occur in 50% of cases 3 to 14 times a month, followed by 15 to 30 times monthly (44.7%); its average duration is 4 to 72 hours in 64.1% of patients. The prodrome with the highest prevalence in the research were the scotomas (78.9%). Its most frequent triggering factors were stress (60.5%), food (32.6%) and sleep (32.6%); among the foods, coffee and chocolate (35.7% and 28.6%, respectively) were the most prevalent. In the morbid antecedents, systemic arterial hypertension and psychiatric diseases were the most mentioned in this study (41.9% and 38.7%, respectively). Among the most frequently mentioned life habits during non-pharmacological treatment, the therapeutic activity prevailed (55%). Of the patients evaluated, 40% of evasion was observed after the first return visit. There was little filling of the headache diary (34%). The prevalence of the main drugs used in prophylactic therapy were tricyclic derivatives (77%), topiramato (23%), flunarizine (9.5%) and propranolol (11.5%). It was noted that 66.6% of the patients were using abusive analgesics before treatment. Conclusion: The main benefits of this study for the CEMEC-CESUPA outpatient clinic of Neurology are the contribution of the scientific analysis to the elaboration of adherence strategies for the patients treated in this clinic and the elaboration of a proposal for a headache diary.
Perfil clínico-epidemiológico dos pacientes diagnosticados com cefaleias primárias atendidos no ambulatório de neurologia do Centro de Especialidades Médicas do CESUPA (CEMEC)
(Centro Universitário do Estado do Pará, 2020) Cardoso, Antônio Augusto Moreira; Silva, Marcos Vinicius Amorim; Penha, Nelson Elias Abrahão da; Souza, Aline Cristine Passos de; http://lattes.cnpq.br/5404002728453981; http://lattes.cnpq.br/5207645183090927
Headache, as a disease, often generates uncertainties in the professionals involved in the consultations, due to the numerous forms of presentation regarding the clinical condition of patients. In this context, the importance of knowing homogeneous characteristics of the local population served, can provide the most agile and effective therapeutic conduct, contributing to the well-being of patients. The aim of this study was to present a clinical-epidemiological profile of patients seen at the Neurology outpatient clinic of the CESUPA Medical Specialties Center (CEMEC), in the period from the first semester of 2017 to the first semester of 2019, diagnosed with different types of primary headaches, through the analysis of medical records. The study design prioritized the collection and analysis of data, established in the research protocol, in the referred location, referring to patients diagnosed with primary headaches: Migraine, Tensional and Trigeminal Autonomic. These results were tabulated and graphs were generated for a better perception of the general picture, the relative risk (odds ratio) was calculated to establish the chances of the sample population to develop the pathology associated with the most prevalent comorbidities. The results were based on 81 medical records of patients with diagnoses among primary headaches, which demonstrated that the majority presented tension headache, followed by migraine, in a larger population of women, between 19 and 60 years old, the main associated comorbidity was hypertension. systemic arterial (0.4: 1) followed by dyslipidemia / Diabetes Mellitus (0.25: 1), the most widely used prophylaxis was ibuprofen, however, most of the sample is untreated. The results of this work were presented in accordance with others already published, with regard to the epidemiological profile of the sample population, the understanding of the association between the types of primary headache and the associated comorbidities proved to be important for the understanding of the causal nexus of the most common etiologies associated with headache. Further research associating the correct diagnosis of headache with the treatment employed and associated diseases may provide better patient management and management.
Relação de polimorfismos genéticos específicos como fatores de risco para o desenvolvimento de Malformações Arteriovenosas (MAVs) cerebrais: uma revisão sistemática
(Centro Universitário do Estado do Pará, 2019) Santos, Leonardo Magalhães; Farias, Valter Fernando Rodrigues; Paschoal Júnior, Fernando Mendes; Paschoal, Eric Homero Albuquerque; http://lattes.cnpq.br/1593548343125421; http://lattes.cnpq.br/0171195401629428
Arteriovenous Malformations (AVMs) of the brain are vascular lesions that shunt arterial blood directly into a low-resistance system of draining veins without an intervening normal capillary bed. Among the main clinical manifestations (which contribute greatly to the cases of death of this pathology), hemorrhage and seizures are prominent. The pathophysiology of this condition is still poorly understood, but the role of proinflammatory cytokines and genes responsible for these cytokines and cerebral angiogenesis in this process is recognized. The present work aimed to identify the relationship of specific genetic polymorphisms as risk factors for the development of Cerebral Arteriovenous Malformations (AVMs). A systematic review of the literature was performed, using the PRISMA Statement as the research protocol, in the MedLine databse. The terms / descriptors in Health Sciences, in the English language, included in the research of the title were: genetic polymorphism, arteriovenous malformation, single nucleotide polymorphism, genetic linkage, brain arteriovenous malformation, hemorrhage, seizures and headache. Case-control studies were included in this study, where, in the research methodology, the genetic tests used to identify the polymorphism and the presence of AVM in image examination were established. The extraction of articles was done by two authors independently. In all, 208 articles were found, of which only 11 fulfilled the inclusion criteria of this research. The most affected age group was in the range between 35 and 40 years. AVMs, in general, presented with a mean size of 3 to 6 cm. Of the analyzed polymorphisms, all had a direct relationship between having the polymorphism and being an MAV (each with its statistical frequency). And, of the more present clinical manifestations, the hemorrhage was highlighted. It is concluded that more studies should be listed to highlight the role of genetic polymorphisms in this process, in order to improve the therapeutic arsenal to lead this pathology and the prognosis of patients.