Navegando por Assunto "Artrite reumatoide"

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Estratégias nutricionais no tratamento de doenças autoimunes
(Centro Universitário do Estado do Pará, 2022) Malcher, Marina Rodrigues Vieira da Gama; Marques, Simone do Socorro Fernandes; http://lattes.cnpq.br/0651248478895645; Moura, Carla Acatauassú Ferreira de; http://lattes.cnpq.br/4504006993667915; Campos, Jamilie Suelen dos Prazeres; http://lattes.cnpq.br/4508719756740232
The present work seeks to analyze the relationship between diet and autoimune diseases, with regard to dietary strategies that would be relevant for the treatment of diseases in this group, with emphasis on the most found pathologies in relation to nutrition (rheumatoid arthritis, type 1 diabetes, celiac disease, Crohn’s disease, multiple sclerosis, systemic lupus erythematosus, psoriasis, Hashimoto’s thyroiditis and vitiligo) by the investigation of existing scientific articles on the subject. This is a study with an exploratory objective, based on a narrative literature review, of a basic nature. Sixteen articles were analyzed, which demonstrated that the food strategies most related to autoimmune diseases, with improvement of symptoms, are diets with an anti-inflammatory pattern or diets that modulate the intestinal microbiota. There also is: Low-carbohydrate Diet, Gluten-free Diet, Semi-vegetarian Diet, Balanced Diet (associated with dietary supplementation of various macronutrients), Low-FODMAP Diet, and Paleolithic Diet with modifications. The dietary strategies under study showed several positive effects on related autoimmune diseases, such as improvement in the associated symptoms, reduction of the inflammatory profile, and, in some cases, remission. However, most articles conclude that more studies are needed to attribute the benefits found to the strategies used.
Prevalência de infecções em pacientes com doenças reumatológicas em tratamento com imunossupressores
(Centro Universitário do Estado do Pará, 2023-05-31) Alves, Gabriel Collares; Grandi, Natalia Crespo; Lima, Glauce Leão; http://lattes.cnpq.br/7526159894502830; Silva, Mariana do Socorro Quaresma; Yoshikawa, Gilberto Toshimitsu; http://lattes.cnpq.br/6926414747469197
Introduction: Rheumatoid Arthritis (RA) and Systemic Lupus Erythematosus (SLE) are chronic, systemic and autoimmune diseases that are very frequent in rheumatology outpatient clinics. Because of the involvement of the immune system by the disease itself and the state of immunosuppression that can be caused by the treatment of such diseases, it can have a great influence on the course of infectious diseases. Objective: Analyze the prevalence and outcome of infectious diseases in patients with rheumatic diseases using immunosuppressive treatments. Methods: It was performed an observational, cross-sectional, descriptive and analytical study. The study sample consisted of patients treated at the CEMEC rheumatology clinic on the days referring to patients with more severe manifestations of the diseases, during the period from September 2022 to January 2023. All tests were performed with the aid of the Bioestat software 5.5. Quantitative variables were described by minimum, maximum, mean, median and standard deviation and qualitative variables by frequency and percentage, with a significance level of 0.05 being defined. Results: The urinary tract infection (UTI) was the most recurrent infection in both analyzed pathologies, followed by lower airway infections. In patients with SLE, candidiasis had an epidemiological significance. The most frequent etiological agents were bacteria, fungus and viruses, respectively. There was no association between the use of immunobiologicals and the incidence of infectious episodes. There was a correlation between RA and osteoporosis. Conclusion: There was an important prevalence of rheumatological diseases and infectious conditions, mainly UTIs, and candidiasis was largely related to SLE. There was no relevant association between the most potent immunosuppressants and hospitalizations. In the study, the main difficulty was inconstancy in filling out information in the medical records, useful for understanding the clinical and pathological characteristics of patients, which could be applied to improve prevention and conduct in the face of infections. It is therefore understood the relevance of filling in the patient's vaccination status, as well as the DAS-28 classification for future studies comparing disease activity with the incidence of infection.
Principais aspectos clínicos e radiológicos pulmonares em pacientes portadores de artrite reumatóide em um Centro de Especialidades Médicas em Belém-PA
(Centro Universitário do Estado do Pará, 2019) Castro, Erick Garcia; Fernandes, Marina Assis da Escóssia; Monteiro, José Tadeu Colares; Ohashi, Claudia Barros; http://lattes.cnpq.br/0889116450004563; http://lattes.cnpq.br/7627103187307808
Objective: To analyze the main repercussions pulmonary, clinical and radiological, in patients diagnosed with rheumatoid arthritis who are being monitored by the Center for Medical Specialties of the Pará State University Center (CEMEC-CESUPA), and from there serve as a source for secondary studies. Methods: The study is cross-sectional, descriptive and observational with quantitative and qualitative descriptive and analytical approach, with data collection in the medical records of patients treated at the Center of Medical Specialties of the University Center of the State of Pará (CESUPA), in the period between january 2014 to december 2018. Results: 156 patients with rheumatoid arthritis were analyzed. The age group and the most affected sex were, respectively, patients older than 60 years and female. Regarding smoking, 53.8% non-smokers, 37.2% former smokers and 9% smokers. Regarding the performance or not of laboratory tests, it was found that 56.4% of the patients performed PPD, 83.3% of the DAS 28 was calculated and 99.4% of the rheumatoid factor. Among the pulmonary symptoms present in 40 patients (24.5%), the most common was dyspnea, followed by chest pain and cough. Regarding the imaging exams, it was concluded that 85.3% had documented in the medical records the description of chest radiography or computed tomography or magnetic resonance, among them, 30.8% presented alteration in the exam. The main documented radiological alteration was the acinar pattern present in 75.0% of patients with alteration, followed by interstitial pattern (66.7%), pulmonary nodule (27.1), pleural pattern (10.4%) and others. Conclusion: It is necessary to perform the analysis of all patients with rheumatoid arthritis, with special attention to pulmonary repercussions due to the significant appearance of clinical and / or radiological alterations in these patients.