Pós-Graduação

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Navegando Pós-Graduação por Orientador "Menezes, Silvio Augusto Fernandes de"

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    Análise da atividade microbiana do extrato de Lippia thymoide, frente a cepa de p. intermediária
    (Centro Universitário do Estado do Pará, 2018) Carvalho, Tábata Resque Beckmann; Menezes, Silvio Augusto Fernandes de; http://lattes.cnpq.br/5394614146901551; Brito, Mileide da Paz; http://lattes.cnpq.br/3493897351649944; Carvalho Junior, Raul Nunes de; http://lattes.cnpq.br/5544305606838748
    Lippia Thymoide (LT) is used in Western medicine to treat respiratory infections, periodontal diseases and periodontal diseases, anti-inflammatory, antibiotic, among others that are related in the literature, the objective of this study is to evaluate the chemical composition of essential oil of Lippia Thymoide and its antimicrobial activity against Prevotella Intermediate (PI) strains and the prevalence of the diagnosis of periodontal diseases. Methodology: the hydrodistilation process was identified and tested through a Minimum Inhibitory Concentration (MIC) test and resistance test against a bacterium. Results: The essential oil of an anti-inflammatory diet relative to pre-medial periodontopathogenic interactions is 6.5 μg / ml and a positive capacity test. Conclusion: the results found in our research demonstrated that the oil of LT, dependent on seasonality, are promising, are a great bacterial potential and becomes a great ally for the manufacture of products that complement the treatment of periodontal diseases
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    Análise da IL-10 em pacientes portadores do HIV-1 com periodontite crônica no norte do Brasil
    (Centro Universitário do Estado do Pará, 2018-03-09) Fonseca, Ricardo Roberto Souza; Menezes, Silvio Augusto Fernandes de; http://lattes.cnpq.br/5394614146901551; Celestino Júnior, Aluísio Ferreira; http://lattes.cnpq.br/6186863425175415; Rodrigues, Tânia Maria de Souza; http://lattes.cnpq.br/4924941383324071
    Aim: The objective of this study was to investigate the levels of IL-10 in the gingival crevicular fluid in HIV-1 positive patients with chronic periodontitis and to compare with HIV-1 negative patients with chronic periodontitis, also to correlate clinical periodontal parameters, viral load and count of CD4+ and CD8+ lymphocytes (LTCD4+ and LTCD8+). Methods: 33 patients were selected and splitted into two groups: 16 HIV-1 positive patients and 17 HIV-1 negative patients and all with chronic periodontitis. The clinical periodontal parameters recorded were: Probing Depth (PD) and Clinical Attachment Level (CAL); the sistemical parameters LTCD4+, LTCD8+ and viral load were analized by the gingival crevicular fluid collected from all patients. Enzymelinked immunosorbent assay (ELISA) was used to determine the concentrations of Interleukin (IL)-10. For the statistical analysis the Student t, Mann-Whitney and Spearman tests were performed. IL-10 levels were significantly lower in both patients groups. Results: There was statistical difference betwen groups for probing depth (p=0.015) and clinical attachment level (p=0.011), no significant correlation was found among the analyzed variables. Conclusion: The IL-10 levels in HIV-1 positive patients had no influence in periodontal and immonological parameters.